Results 1 to 10 of about 2,068,101 (118)

A Cross-sectional Study on the Electrophysiological Profile of Leprosy Patients in a Tertiary Care Institute in Chhattisgarh, India [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Leprosy is a bacterial infection caused by Mycobacterium leprae. It mainly infects skin, mucosa and nerves. Neural involvement is primarily due to the selective affinity of Schwann cells for lepra bacilli.
Rakesh Kumar Patel, Mitesh Kumar Sinha, Sa Dilip Kumar, Akhilesh Behra   +3 more
doaj   +1 more source

Rapid Plasma Reagin Card Test: A Screening Method for Syphilis in Antenatal Patients of Bastar, Chhattisgarh, India [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Sexually Transmitted Disease (STD) like syphilis is one of the important factor leading to adverse pregnancy outcomes in antenatal mothers.
Sahina Hassan, Satyaram Satapathy, Ratna Agrawal   +2 more
doaj   +1 more source

Cadaver as the first silent medical teacher: Exploring bioethical perceptions of department of anatomy

Asian Journal of Medical Sciences, 2022
Background: Department of Anatomy with its time honored and integral essence, human cadaveric dissection has been trying to serve the medical profession since the inception of medicine.
Surajit Kundu , Anil R Sherke, Richa Gurudiwan   +2 more
doaj   +1 more source

NAVIGATOR: a phase 3 multicentre, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the efficacy and safety of tezepelumab in adults and adolescents with severe, uncontrolled asthma

Respiratory Research, 2020
Background Patients with severe, uncontrolled asthma have a significant unmet need for new treatments that have broader effects on airway inflammation, and that provide greater improvements in asthma outcomes than currently approved biologics and ...
Andrew Menzies-Gow, Gene Colice, Janet M. Griffiths, Gun Almqvist, Sandhia Ponnarambil, Primal Kaur, Gennaro Ruberto, Karin Bowen, Åsa Hellqvist, May Mo, Esther Garcia Gil   +10 more
doaj   +1 more source

DESTINATION: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the long-term safety and tolerability of tezepelumab in adults and adolescents with severe, uncontrolled asthma

Respiratory Research, 2020
Background Tezepelumab is a human monoclonal antibody that blocks the activity of the epithelial cytokine thymic stromal lymphopoietin. The efficacy, safety and oral corticosteroid-sparing potential of tezepelumab are being investigated in two ongoing ...
Andrew Menzies-Gow, Sandhia Ponnarambil, John Downie, Karin Bowen, Åsa Hellqvist, Gene Colice   +5 more
doaj   +1 more source

A study of high neuroticism in long-term survivors of childhood, adolescence, and young adult cancers

Scientific Reports, 2022
Neuroticism is a basic personality trait concerning negative feelings under stressful conditions. Our purpose was to examine the rate of high neuroticism and factors associated with high neuroticism in long-term (≥ 5 years) survivors of childhood ...
Alv A. Dahl, Cecilie Essholt Kiserud, Sophie D. Fosså, Jon Håvard Loge, Kristin Valborg Reinertsen, Ellen Ruud, Hanne C. Lie   +6 more
doaj   +1 more source

Effect of Tezepelumab on the Humoral Immune Response to Seasonal Quadrivalent Influenza Vaccination in Patients with Moderate to Severe Asthma: The Phase 3b VECTOR Study

Pulmonary Therapy, 2023
Introduction Annual influenza vaccinations are recommended for adolescents and adults with moderate to severe asthma. This study investigated the effect of tezepelumab, a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin,
Jeremy Cole, Iwona Cąpała-Szczurko, Stephanie Roseti, Claudia Chen, Scott Caveney, Anastasia A. Aksyuk, Katie Streicher, Sandhia Ponnarambil, Gene Colice   +8 more
doaj   +1 more source

Where Were Court Cases Heard in Northern Iberia in the Early Middle Ages and Were These Community Places?

Reti Medievali Rivista, 2023
There is some good, though limited, evidence of community space in northern Iberia in the later tenth century. These are the spatial zones defined by the remit of local meetings at which business was transacted.
Wendy Davies
doaj   +1 more source

Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response

Communications Biology, 2023
The Schlafen (SLFN)11 gene has been implicated in various biological processes such as suppression of HIV replication, replication stress response, and sensitization of cancer cells to chemotherapy.
Erin Alvi, Ayako L. Mochizuki, Yoko Katsuki, Minori Ogawa, Fei Qi, Yusuke Okamoto, Minoru Takata, Anfeng Mu   +7 more
doaj   +1 more source

SOURCE: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel group trial to evaluate the efficacy and safety of tezepelumab in reducing oral corticosteroid use in adults with oral corticosteroid dependent asthma

Respiratory Research, 2020
Background Many patients with severe asthma continue to experience asthma symptoms and exacerbations despite standard-of-care treatment. A substantial proportion of these patients require long-term treatment with oral corticosteroids (OCS), often at high
Michael E. Wechsler, Gene Colice, Janet M. Griffiths, Gun Almqvist, Tor Skärby, Teresa Piechowiak, Primal Kaur, Karin Bowen, Åsa Hellqvist, May Mo, Esther Garcia Gil   +10 more
doaj   +1 more source