Results 201 to 210 of about 2,604,224 (268)

Senescence in Normal Human Dermal Fibroblasts Induces Heterogeneous Fibril Orientation of Type I Collagen Through Downregulation of BMP-1. [PDF]

Genes Cells
Moriya K, Shibaike Y, Sano K, Tanaka T.
europepmc   +1 more source

Coping with the Unknown: Scribes and the Transmission of Scientific Texts in Late Medieval England (York, York Minster Chapter Library, MS. XVI E. 32: a Case Study)

Rebeca Cubas-Peña
openalex   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Supporting Information for: Low-latitude weathering fluctuations drove the Late Paleozoic glaciation-deglaciation transition

Min Zhang, Hongliang Lu, Tingwei Zhang, Bitian Wei, Yifei Hou, Pingyuan Shi, J. Fang, Yingchao XU, Huafeng Qin, Chenglong Deng, Shu-Zhong Shen, Yongxin Pan   +11 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Impact of adverse postnatal environment on emotional regulation and neuroimmune function in adolescent rats prenatally exposed to alcohol. [PDF]

Neurobiol Stress
Holman PJ, Vella VR, Baglot SL, Yeates D, Ubi P, Weinberg J, Bodnar TS, Raineki C.   +7 more
europepmc   +1 more source

Time as Phase Flow IV: Observational Signatures and Falsifiability in Late-Time Cosmology

Pruk Ninsook
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Late breast implant infection after severe pneumonia - a case report and literature review. [PDF]

Case Reports Plast Surg Hand Surg
Segura E, Oyonate H, García Barón P, Escrigas F, Descarrega J, Fontdevila J.   +5 more
europepmc   +1 more source