Results 1 to 10 of about 281 (95)

DFT‐Guided Design of a Multi‐Enzyme Mimetic High‐Entropy Nanozyme for Cascaded Glutathione Detection and Point‐of‐Care Testing [PDF]

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Guided by density functional theory (DFT) calculations, a MnCoNiCuZnFe‐based Prussian blue analog (HEO) is screened out. It exhibits superior peroxidase (POD)‐like activity compared to noble metal‐incorporated high‐entropy nanozymes together with excellent oxidase (OXD) and glutathione oxidase (GSHOx)‐like activities.
Hua Lin, Li Ke, Shuran Wang, Ruoke Li, Shengmin Zhou, Yueling Liu, Huan Pang   +6 more
wiley   +2 more sources

Breaking the Selectivity Barrier of Single‐Atom Nanozymes Through Out‐of‐Plane Ligand Coordination [PDF]

Advanced Materials, Volume 37, Issue 38, September 25, 2025.
Here, Ru SAzyme with out‐of‐plane chlorine ligands is reported as a monofunctional, high‐performance peroxidase‐like nanozyme. Incorporating out‐of‐plane ligand coordination emulates enzyme selectivity and regulates reaction pathways for an identical substrate.
Seonhye Park, Kyu In Shim, Phuong Thy Nguyen, Daeeun Choi, Seongbeen Kim, Seung Yeop Yi, Moon Il Kim, Jeong Woo Han, Jinwoo Lee   +8 more
wiley   +2 more sources

Monolayer graphene/platinum-modified 3D origami microfluidic paper-based biosensor for smartphone-assisted biomarkers detection

ADMET and DMPK
Background and purpose: Imbalances in biomarkers such as dopamine and NADH are linked to neurological and metabolic disorders, including Parkinson’s disease, depression, and stroke, underscoring the need for rapid and accessible diagnostics.
Arda Fridua Putra, Annisa Septyana Ningrum, Suyanto Suyanto, Vania Mitha Pratiwi, Muhammad Yusuf Hakim Widianto, Irkham Irkham, Wulan Tri Wahyuni, Isnaini Rahmawati, Fu-Ming Wang, Chi-Hsien Huang, Ruri Agung Wahyuono   +10 more
doaj   +1 more source

Stress Echocardiography to Detect Exercise Pulmonary Hypertension in Patients With Chronic Thromboembolic Pulmonary Disease

Pulmonary Medicine, Volume 2026, Issue 1, 2026.
Background This study was aimed at determining whether stress echocardiography could detect exercise pulmonary hypertension (ePH) in patients with mild chronic thromboembolic pulmonary disease (CTEPD) as compared with right‐heart catheterization (RHC).
Adam Dhayyat, Knut Stavem, Øyvind Jervan, Janne Mykland Hilde, Diyar Rashid, Jostein Gleditsch, Waleed Ghanima, Kjetil Steine, Nidhi Chaudhary   +8 more
wiley   +1 more source

From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways

Advanced Sensor Research, Volume 4, Issue 10, October 2025.
Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley   +1 more source

Fabrication, Flow Control, and Applications of Microfluidic Paper-Based Analytical Devices

Molecules, 2019
Paper-based microfluidic devices have advanced significantly in recent years as they are affordable, automated with capillary action, portable, and biodegradable diagnostic platforms for a variety of health, environmental, and food quality applications ...
Hosub Lim, Ali Turab Jafry, Jinkee Lee
doaj   +1 more source

Electrochemical Biosensors for Cancer Biomarker Detection: Basic Concept, Design Strategy and Cutting‐Edge Development

Electrochemical Science Advances, Volume 5, Issue 5, October 2025.
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley   +1 more source

Illuminating the Unseen: Dynamic Butyrylcholinesterase Detection Driving Precision Medicine and Environmental Toxicology

SmartMat, Volume 6, Issue 5, October 2025.
Butyrylcholinesterase (BChE), a key member of the cholinesterase family, plays an indispensable role in neural signal regulation, Alzheimer's disease therapeutic development, metabolic homeostasis, and clinical toxicology diagnostics. This study provides a comprehensive review of existing analytical methodologies for BChE detection, along with their ...
Min Liu, Shuaige Bai, Shuai Huang, Ting Luo, Yiyang Zhou, Meihui Liu, Xueping Feng, Wenbin Zeng   +7 more
wiley   +1 more source

Applications of artificial intelligence‐driven microfluidics in medical laboratory science

Interdisciplinary Medicine, Volume 3, Issue 5, September 2025.
The advancements in microfluidics and artificial intelligence are transforming the landscape of Medical Laboratory Science. This article systematically reviews the approaches and applications of AI‐driven microfluidics for analyzing cells, bacteria, nucleic acids, proteins, viruses, and cancer, while also addressing current challenges and proposing ...
Qingyang Jiang, Qiaohui Mo, Chenchen Ge, Wangjing Li, Jingwen Mai, Yao Chen, Ying Liu, Xiaoyan Deng, Zifeng Yang, Dou Wang   +9 more
wiley   +1 more source

Next-generation immuno-biosensors: Transforming foodborne pathogen detection

Talanta Open
The persistent threat of foodborne pathogens, despite safety measures, underscores the urgent need for highly sensitive and rapid sensing technologies to prevent outbreaks and mitigate their devastating health and economic impacts.
Sana Ahmed, Park Tusan
doaj   +1 more source