Results 71 to 80 of about 669 (134)

PCANN Program for Structure‐Based Prediction of Protein–Protein Binding Affinity: Comparison With Other Neural‐Network Predictors

Proteins: Structure, Function, and Bioinformatics, Volume 93, Issue 9, Page 1498-1506, September 2025.
ABSTRACT In this communication, we introduce a new structure‐based affinity predictor for protein–protein complexes. This predictor, dubbed PCANN (Protein Complex Affinity by Neural Network), uses the ESM‐2 language model to encode the information about protein binding interfaces and graph attention network (GAT) to parlay this information into Kd ...
Olga O. Lebedenko, Mikhail S. Polovinkin, Anastasiia A. Kazovskaia, Nikolai R. Skrynnikov   +3 more
wiley   +1 more source

Produção e caracterização da fusão ZZapo-CBM64 para captura e deteção da apolipoproteína-A1 em testes de papel [PDF]

, 2019
Mestrado em Bioquímica - Métodos BiomolecularesAffibodies (ZZ) são pequenas proteínas de afinidade que podem ser modificadas para se ligarem a alvos específicos. Estas proteínas têm sido sugeridas como uma alternativa a anticorpos, devido ao seu processo
Barbosa, Luís Miguel Marques
core  

The Role of Artificial Intelligence in Advancing Biosensor Technology: Past, Present, and Future Perspectives

Advanced Materials, Volume 37, Issue 34, August 28, 2025.
This review explores the transformative role of AI in biosensor technology and provides a holistic interdisciplinary perspective that covers a broader scope of AI‐enabled biosensor technologies across various sectors including healthcare, environmental monitoring, food safety, and agriculture. It also highlights the important role of novel materials in
Tuğba Akkaş, Mahshid Reshadsedghi, Mustafa Şen, Volkan Kılıç, Nesrin Horzum   +4 more
wiley   +1 more source

Electrochemical Determination of Gallic Acid in Tea Samples Using Pyramidal Pt Nanoparticles

Advanced Electronic Materials, Volume 11, Issue 8, June 2025.
A novel electrochemical sensor based on pyramidal Pt nanoparticles for gallic acid detection in black and green tea samples is developed. The sensor is prepared by a simple drop casting of nanoparticles on the electrode surface, without any supporting materials, such as polymer matrices and surfactants.
Tiziano Di Giulio, Maria Antonieta Ramírez‐Morales, Valentina Mastronardi, Giuseppe Mele, Rosaria Brescia, Pier Paolo Pompa, Cosimino Malitesta, Giuseppe Egidio De Benedetto, Mauro Moglianetti, Maria Ada Malvindi, Elisabetta Mazzotta   +10 more
wiley   +1 more source

An Overview of Microfluidic‐Assisted Strategies for Synthesis and Applications of Molecularly Imprinted Polymers

Analysis &Sensing, Volume 5, Issue 3, May 2025.
Sensor design increasingly focusses on miniaturized systems deployed directly at the point of need. For this purpose, microfluidics ensures low‐cost systems that can handle small sample volumes and molecularly imprinted polymers provide rugged, cost‐effective recognition.
Ramya Karunakaran, Chiara Luna Onorati, Khairunnisa Amreen, Sanket Goel, Peter A. Lieberzeit   +4 more
wiley   +1 more source

Aptasensor‐based point‐of‐care detection of cardiac troponin biomarkers for diagnosis of acute myocardial infarction

The Kaohsiung Journal of Medical Sciences, Volume 41, Issue 3, March 2025.
Abstract Acute myocardial infarction (AMI) represents a critical health challenge characterized by a significant reduction in blood flow to the heart, leading to high rates of mortality and morbidity. Cardiac troponins, specifically cardiac troponin I and cardiac troponin T, are essential proteins involved in cardiac muscle contraction and serve as ...
Tharmaraj Vairaperumal, Ping‐Yen Liu
wiley   +1 more source

Next-generation immuno-biosensors: Transforming foodborne pathogen detection

Talanta Open
The persistent threat of foodborne pathogens, despite safety measures, underscores the urgent need for highly sensitive and rapid sensing technologies to prevent outbreaks and mitigate their devastating health and economic impacts.
Sana Ahmed, Park Tusan
doaj   +1 more source

Design of a disposable µPAD for on-hand quantification of urinary creatinine [PDF]

, 2022
In this work, a new microfluidic paper-based analytical device (μPAD) was developed for on-hand creatinine quantification in urine samples. This is clinically significant since creatinine monitorization in urine is an indicator of health condition, as ...
Melo, Maria M. P., Mesquita, Raquel B. R., Rangel, António O. S. S.   +2 more
core  

Optical Bionanosensors for Sepsis Diagnostics

Small, Volume 21, Issue 8, February 25, 2025.
Sepsis is a global health issue triggered by an uncontrolled immune response to infections, causing organ failure and high mortality. Despite advances in medical care, traditional diagnostic methods are still not sufficient. This review highlights recent advancements in nanomaterial‐based optical biosensors for rapid sepsis diagnostics, discussing ...
Christina Derichsweiler, Svenja Herbertz, Sebastian Kruss   +2 more
wiley   +1 more source

Aptamer and DNAzyme Based Colorimetric Biosensors for Pathogen Detection

Angewandte Chemie, Volume 137, Issue 4, January 21, 2025.
Pathogen detection is crucial for preventing and managing health risks. This review consolidates the selection of functional nucleic acids (FNAs) for pathogen detection and the development of cost‐effective, simple diagnostic applications. It focuses on integrating FNAs with gold nanoparticles, polydiacetylenes, protein enzymes, G‐quadruplexes, and ...
Rudi Liu, Jiuxing Li, Bruno J. Salena, Yingfu Li   +3 more
wiley   +1 more source