Results 201 to 210 of about 846,543 (267)

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Understanding contemporary challenges to safe abortion access in Africa through a health systems lens: a systematic review protocol. [PDF]

BMJ Open
Agula C, Kanmiki EW, Ofori CAE, Ogunoye O, Church K, Ouedraogo R, Bawah AA.   +6 more
europepmc   +1 more source

Kenyan Farmers' Policy Priorities During Economic Crisis and Stability: Insights From a Best‐Worst Scaling Experiment

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Amid rising food and fertilizer prices, understanding farmers' policy preferences is critical for effective crisis response. We use best‐worst scaling experiment to assess Kenyan mobile‐owning crop farmers' preferences for government support under high and normal price scenarios.
Mywish K. Maredia, John Olwande, Jacob Ricker‐Gilbert, David L. Mather, Nicole M. Mason   +4 more
wiley   +1 more source

Revisiting the African mtDNA landscape through complete mitochondrial genomes. [PDF]

Commun Biol
Lankheet I, Chowdhury A, Tellgren-Roth C, Jolly C, Soares AER, de Navascués M, Pacchiarotti S, Maselli L, Kouarata G, Donzo JP, Coetzee V, de Castro M, Ebbesen P, Priehodová E, Podgorná E, Černý V, Green ST, Harena P, Bakrobena L, Fomine FLM, Tolesa ZG, Mengesha WA, de Jongh M, Soodyall H, Bostoen K, Barbieri C, Larena M, Malmström H, Schlebusch CM.   +28 more
europepmc   +1 more source

Sustainable Productivity Growth in Agriculture: The Role of Shifts in R&D Investments and Technology

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT The objective of the paper is to evaluate the long‐term prospects of sustainable productivity growth linked to plausible assumptions on public agricultural R&D investments as the key productivity driver. Second, it investigates the role of changing R&D focus from yield maximization to input saving technologies (fertilizers and pesticides). The
Zuzana Smeets Křístková, Michiel van Dijk, Robert M'Barek, Hans van Meijl, Tomas Ratinger   +4 more
wiley   +1 more source

Dossier Día de África 2020 [PDF]

, 2020
Molfino, Santiago, Baravalle, Bruno, Sobral, Lucía, Jorge, Martín, Schiro, Manuel, Morasso, Carla (Coord.), Marchetti, Agustina (Coord.), Acosta, Agustina Vienna, Franz, Katerina, Martín, Paula   +9 more
core  

The need for sustaining mpox vaccination in Africa. [PDF]

Nat Commun
Boum Y, Doshi RH, Ibeneme CU, Nsasiirwe S, Dereje N, Njenge H, Vilajeliu A, Balde T, Ngongo N, Kaseya J, Lewis RF.   +10 more
europepmc   +1 more source

Coping With Production Risk: Effects of Sown Plant Diversity on the Attractiveness of Crop Insurance in Grasslands

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Increased frequency of extreme weather events, particularly droughts, threatens grassland farming by destabilizing yields and farms' economic viability. We examine, theoretically and through numerical simulations, how sown plant diversity (natural insurance) influences the attractiveness of indemnity and drought index insurance (formal ...
Nicolas Alou, Sergei Schaub, Martin Quaas, Robert Finger   +3 more
wiley   +1 more source

Patterns of Infectious Disease Identified in Clinical Autopsy at a South African Tertiary Care Setting: A 10-Year Retrospective Study. [PDF]

Diseases
Khaba MC, Dikotope M, Nkwagatse T, Maphoto R, Manzini T, Maaga K, Makhado NA.   +6 more
europepmc   +1 more source

Assessing Household Welfare in Response to Rising Food Prices in The Gambia

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study examines how rising food prices affected household welfare in The Gambia using nationally representative data from the 2015/16 Integrated Household Survey (IHS‐3). The analysis reflects household consumption behavior and market conditions prevailing during that period and provides a structural benchmark for understanding ...
Roger Vorsah, Obed Quaicoe, Fafanyo Asiseh, John N. Ng'ombe   +3 more
wiley   +1 more source