Results 101 to 110 of about 672,847 (238)
Advanced Science, EarlyView.Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go +12 more
wiley +1 more source
Teaching Partial Differential Equations with CAS [PDF]
, 2018 Partial Differential Equations (PDE) are one of the topics where Engineering students find more difficulties when facing Math subjects. A basic course in Partial Differential Equations (PDE) in Engineering, usually deals at least, with the following ...
Aguilera-Venegas, Gabriel +5 more
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Advanced Science, EarlyView.A transfer‐free fabrication method enables multilayer graphene microelectrodes as small as 10 µm, eliminating reliability issues of manual graphene transfer. These electrodes record neural activity in brain slices with exceptional signal‐to‐noise ratios (up to 25–40 dB) while maintaining optical transparency for multimodal applications.
Nerea de Alvarez de Eulate +7 more
wiley +1 more source
Comienzos de la catequesis en América y particularmente en Chile (Reseña) [PDF]
, 1993 Reseña del libro de Enrique GARCÍA AHUMADA, Comienzos de la catequesis en América y particularmente en Chile, Seminario Pontificio Mayor de los Santos Ángeles Custodios («V Centenario»), Santiago de Chile 1991, 720 ...
Saranyana, J.I. (Josep Ignasi)
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Advanced Science, EarlyView.Machine learning models predict in real time the onset of harmful microbubble collapse during microbubble‐enhanced focused ultrasound (MB‐FUS) and enable dynamic adjustment of sonication to prevent cavitation‐induced damage. This predictive control expands the safe operating window for bloodbrain barrier opening, enhancing nanoparticle delivery and ...
Hohyun Lee +17 more
wiley +1 more source
Book Review Essay: The Mature Phase: Four Generations of Scholarship on Colonial Mesoamerica and New Spain [PDF]
, 2018 This essay reviews the following works: Native Wills from the Colonial Americas: Dead Giveaways in a New World. Edited by Mark Christensen and Jonathan Truitt. Salt Lake City: University of Utah Press, 2016. Pp. vii + 276. $55.00 cloth.
Matthew, Laura E.
core +1 more source
Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases
Advanced Science, EarlyView.Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim +8 more
wiley +1 more source
Revista de Gastroenterología de México (English Edition)Introduction and aims: Neuroendocrine neoplasms are rare tumors accounting for approximately 2% of all neoplasms, most of which (62–70%) originate in the gastrointestinal tract and pancreas.
R. Sánchez-Arreguín +4 more
doaj +1 more source
Advanced Science, EarlyView.Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin +10 more
wiley +1 more source
SiembraLos hongos endófitos [HE] son microorganismos que viven dentro de las plantas sin causar daño aparente, y colaboran en la síntesis de sustancias reguladoras del crecimiento, fijación de nitrógeno, protección contra patógenos, entre otros beneficios para
Carolina Díaz-Valenzuela +3 more
doaj +1 more source