Results 71 to 80 of about 455,438 (246)
, 2020 Entrevista a la Dra. Ángeles Zorreguieta en el marco del proyecto Houssay y Leloir.OriginalFil: Zorreguieta, Ángeles.ColorMatías A. Loewy (Entrevista); Esteban D.
Zorreguieta, Ángeles
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Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Frontiers in EducationUniversity education encourages the development of rigorous scientific research, making it essential to improve redaction skills. Therefore, this research evaluates the impact of the strategic use of Artificial Intelligence (AI)—including applications ...
Nilo Albert Velásquez Castillo +4 more
doaj +1 more source
, 2014 Esta obra, coordinada por las profesoras Mª Ángeles Goicoechea y María José Clavo, de la Universidad de La Rioja, acopia parte de la intensa tarea acometida por las integrantes del Grupo de Investigación “Igualdad y Género”, de esa misma Universidad, en ...
Valdemoros San Emeterio, María Ángeles [0000-0002-7389-4039]
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Advanced Science, EarlyView.ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu +10 more
wiley +1 more source
Advanced Science, EarlyView.MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou +21 more
wiley +1 more source
Factores pronósticos del síndrome de exanguinación para el control de lesiones
Revista Colombiana de Cirugía, 2007 Introducción: El trauma es una epidemia en las sociedades modernas. La causa de muerte más frecuente en pacientes traumatizados es la pérdida masiva de sangre, lo cual puede ocurrir en el lugar mismo del trauma o después de aplicar medidas de ...
Patrizio Petrone +4 more
doaj
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
Advanced Science, EarlyView.We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Traumatismos de páncreas: diagnóstico y tratamiento
Revista Colombiana de Cirugía, 2008 Los traumatismos de páncreas son infrecuentes; representan, aproximadamente, el 4% de las lesiones abdominales pero conllevan una tasa de morbimortalidad significativa, razón por la cual es primordial su reconocimiento y tratamiento precoz.
Patrizio Petrone +4 more
doaj
Advanced Science, EarlyView.Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen +8 more
wiley +1 more source