Results 111 to 120 of about 6,984,629 (288)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Educar para la sociedad informacional: Hacia el multialfabetismo
Revista Portuguesa de Pedagogia, 2008 Este artigo analisa o analfabetismo digital como um dos problemas educacionais decorrentes da chamada sociedade da informação. Identificam-se várias abordagens ou visões sobre a alfabetização digital. Propõe-se o termo multialfabetização como um conceito
Manuel Area Moreira
doaj +1 more source
Bienestar desde tu hogar: crianza positiva
, 2020 Archivo de audioEn esta entrega, el Doctor John Oñate, experto de la Fundación Universitaria del Área Andina da a conocer el decálogo de la crianza positiva en época de ...
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Educar, 2002 Las nuevas tecnologías de la información son un hecho imparable y que reporta importantes y variados beneficios a quienes las utilizan. Sin embargo tienen efectos secundarios perniciosos sobre nuestro sistema social.
Manuel Area Moreira
doaj +1 more source
Representaciones culturales: orquesta Areandina
, 2020 Archivo audiovisual; 2:33 minutos.En este recurso los estudiantes y docentes de la Fundación Universitaria del Área Andina, realizan una demostración artística, con el fin de acompañar el viaje cultural virtual realizado por la ...
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Revista Facultad de Ingeniería Universidad de Antioquia, 2010 Este artículo presenta un método de solución descentralizada para el problema de flujo de potencia AC en sistemas de potencia con áreas interconectadas.
Mauricio Granada Echeverri +2 more
doaj