Results 161 to 170 of about 6,984,629 (288)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Los efectos del modelo 1:1 en el cambio educativo en las escuelas

Revista Iberoamericana de Educación, 2011
n este artículo se ofrece una revisión de los principales hallazgos de los estudios evaluativos sobre el impacto de los modelos 1:1 en el contexto anglosajón y, a partir de los mismos, se enuncia una serie de retos y desafíos para el diseño ...
Manuel Area Moreira
doaj  

Acúmulo de forragem e raízes, perfilhamento e área foliar do capim-Marandu submetido a doses de nitrogênio em solos de diferentes fertilidades

Boletim de Indústria Animal, 2008
Objetivou-se com este trabalho avaliar a produção de matéria seca da parte aérea e raízes, a área foliar e o perfilhamento do capim-Marandú (Brachiaria brizantha (Hochsct ex. A. Rich) Stapf.) cultivado em solo proveniente de área corrigida e adubada e outra não, submetido a diferentes doses de N.
Rosane Cláudia Rodrigues, Valdo Rodrigues Herling, Olga L. Faftine, Mateus Rodrigues Stefano, Luis Pedro de Melo Plese, Pedro Henrique de Cerqueira Luz, Luciano da Silva Cabral   +6 more
openaire   +5 more sources

Representaciones culturales: conjunto vallenato Areandina 

, 2020
1 archivo audiovisual ; 2:31 minutos.En este recurso los estudiantes y docentes de la Fundación Universitaria del Área Andina, realizan una demostración artística, con el fin de acompañar el viaje cultural virtual realizado por la ...

core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Uso de áreas de reserva com cana-de-açucar exclusiva e cana-de açúcar associada à leguminosas, no desempenho de bovinos a pasto

Boletim de Indústria Animal, 2014
O experimento foi conduzido em Pirajuí-SP, com o objetivo de se estudar a viabilidade do uso de áreas de reserva com cana-de-açúcar exclusiva ou consorciada com leguminosas na melhoria do desempenho animal no período crítico do ano, como complemento de pastagens de braquiária humidícola.
Nelson Morato Ferraz Meirelles, Pedro Luis Guárdia Abramides, Dumas Vicente Casagrande, Luiz Carlos Munhoz   +3 more
openaire   +7 more sources

Representaciones culturales: grupo música andina Areandina 

, 2020
1 archivo audiovisual ; 3:30 minutos.En este recurso los estudiantes y docentes de la Fundación Universitaria del Área Andina, realizan una demostración artística, con el fin de acompañar el viaje cultural virtual realizado por la ...

core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Representaciones culturales: grupo danzas Areandina

, 2020
1 archivo audiovisual ; 2:26 minutos.En este recurso los estudiantes y docentes de la Fundación Universitaria del Área Andina, realizan una demostración de danza artística, con el fin de acompañar el viaje cultural virtual realizado por la ...

core