Cellular availability of <i>all-trans</i>-retinoic acid in mice: a pilot study. [PDF]
Yoshihara M +5 more
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Nocturnal Lepidoptera Larvae in Mega-Project: Habitat and Environmental Factors Over Construction Effects. [PDF]
Trombin D +6 more
europepmc +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
A Follow-Up Study After Reduction in an Excessive Intake of Cadmium from Rice on Changes in Blood and Urinary Cadmium Levels and Renal Tubular Function Among Female Farmers in Cadmium-Polluted Areas in Northern Japan. [PDF]
Horiguchi H +4 more
europepmc +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Household environmental management practices, community engagement, and self-reported malaria incidence in urban and rural communities of Malawi. [PDF]
Lungu MM, Davitadze A.
europepmc +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
The Effect of Advanced Platelet-Rich Fibrin on the Healing of Post-Extraction Sockets in Patients with Diabetes: Preliminary Findings from a Randomized Controlled Clinical Trial. [PDF]
Alyafi R +13 more
europepmc +1 more source

