Results 81 to 90 of about 521,624 (218)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

ACUMULACIÓN DE CARBONO Y CAMBIOS ESTRUCTURALES EN BOSQUES SECUNDARIOS DEL ORIENTE ANTIOQUEÑO, COLOMBIA CARBON ACCUMULATION AND STRUCTURAL CHANGES IN SECONDARY FORESTS IN EASTERN ANTIOQUIA, COLOMBIA

Actualidades Biológicas, 2011
En el Oriente antioqueño (Antioquia), Colombia, en tierras utilizadas previamente en ganadería extensiva, se estudió la sucesión secundaria analizando la densidad arbórea, área basal y biomasa aérea.
Miguel A. Peña, Juan Saldarriaga, Álvaro J. Duque-Montoya   +2 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Dinámica espacio-temporal del bosque mesófilo del centro-sur del estado de Jalisco, México

Polibotánica, 2018
Con el objetivo de cuantificar los cambios espacio-temporales de atributos estructurales y de composición florística de especies árboreas del bosque mesófilo de montaña, se establecieron ocho parcelas permanentes de 2,500 m2 cada una.
Enrique Valente Sánchez Rodríguez
doaj  

Exploitation of the Large-Area Basal Plane of MoS₂ and Preparation of Bifunctional Catalysts through On-Surface Self-Assembly. [PDF]

Adv Sci (Weinh), 2017
Zhao Y, Li Q, Shi L, Wang J.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Parameterization of the cultivation density of Austrian Pine, Corsican Pine and Douglas Fire Plantations

Annals of Silvicultural Research
This note presents the application of the maximum stand basal area concept from the Assmann's theory to determine the intensity of thinning of even-aged forest stands.
Piermaria Corona
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

CARACTERIZACIÓN DE ETAPAS DE SUCESIÓN SECUNDARIA EN LA RESERVA NATURAL COCOBOLO, DISTRITO DE CHEPO, PANAMÁ

Tecnociencia, 2010
  En este estudio se describen y se comparan las características de diferentes etapas de sucesión secundaria en la Reserva Natural Cocobolo, localizada en la cuenca alta del río Mamoní, distrito de Chepo.
Jorge A. Mendieta, Emilio R. Espino, Christel A. Ramos   +2 more
doaj