Results 51 to 60 of about 7,544 (146)

Áreas urbanas vulnerables: algunas consideraciones para un sector de Resistencia, Chaco

Cuaderno Urbano, 2007
El proceso de expansión territorial de las últimas décadas de las ciudades del Nordeste Argentino ha provocado, entre otras cosas, ocupación indiscriminada de áreas de alto riesgo tanto hídrico como ambiental.
Marina Scornik
doaj  

Rational Design of Multifunctional Tacrine Derivatives as Candidates for the Treatment of Alzheimer and Parkinson Diseases

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
We present a set of multifunctional tacrine derivatives, designed with the CADMA‐Chem protocol, aimed for Alzheimer and Parkinson diseases. Of the tacrines designed, TAC‐674 and TAC‐678 are the best candidates to act as multifunctional antioxidants and neuroprotectors for Alzheimer and Parkinson diseases, respectively.
Eugenia Dzib, Luis Felipe Hernández‐Ayala, Silvana Silva‐Aguirre, Annia Galano   +3 more
wiley   +1 more source

Mapping Trofinetide Polypharmacology in Rett Syndrome: A Multi‐Stage Computational Analysis

Journal of Computational Chemistry, Volume 47, Issue 21, August 5, 2026.
How can a single molecule address the complex symptoms of Rett syndrome? This computational study maps the multi‐target mechanism of trofinetide, revealing diverse modes of binding across five key receptors: GAT1, GABAA, CHRM1, AMPA, and GSK3β. From deep orthosteric anchoring to dynamic surface interactions, these structural insights provide a rational
Luis Felipe Hernández‐Ayala, Gabriel Eduardo Guzmán‐López, Annia Galano   +2 more
wiley   +1 more source

Testing the Dry Refuge Model: Paleoecological Insights From Late Pleistocene Gomphotheres in Ecuador

Ecology and Evolution, Volume 16, Issue 8, August 2026.
We present paleontological evidence that may prove the Dry Refuge Model in Ecuador during the Late Pleistocene. ABSTRACT Paleoenvironmental records indicate that Neotropical regions near the Equator experienced reduced rainfall during the Last Glacial Maximum (LGM). However, some records show conflicting environmental signals.
Erwin González‐Guarda, Iván Ramírez‐Pedraza, Carlos Tornero, Lidiane Asevedo, Natalia Villavicencio, Sebastián Escobar, José Luis Román, Melissa Hidalgo, Esteban Benalcázar, Florent Rivals   +9 more
wiley   +1 more source

Transesterificación de aceite de canola con Sr/CaO mediante el método Box-Behnken

Mundo Nano
Dada la necesidad de nuevos materiales catalíticos para la transesterificación de aceites para la generación de biodiesel, el objetivo de este trabajo fue optimizar esta reacción usando catalizadores de Sr/CaO obtenidos a partir de cascarón de huevo ...
David Marín-Lugo, Rodrigo Barrera-Gutiérrez, Gabriela Alejandra Vázquez-Rodríguez, Gerardo Chávez-Esquivel, Jesús Andrés Tavizón-Pozos   +4 more
doaj   +1 more source

SÍNTESIS DE HIDROXIFOSFATO DE COBRE BAJO LOS PRINCIPIOS DE LA QUÍMICA VERDE

Avances en Ciencias e Ingeniería, 2021
This work aims to present two syntheses according to the green chemistry principles of Cu2(OH)PO4. The first is a mechanochemical synthesis that was carried out with Cu3(PO4)2 and NaOH at room temperature and without solvent (principles five and six ...
Lilia Fernández-Sánchez, Mirella Gutiérrez-Arzaluz   +1 more
doaj  

Probiotic Stability and Antihypertensive Activity of Peptides in Aguamiel Syrup‐Fortified Milk Protein Fermented by Lacticasebacillus rhamnosus GG

eFood, Volume 7, Issue 4, August 2026.
This study evaluates the impact of aguamiel syrup on a synbiotic fermented dairy product, focusing on antihypertensive peptide release and Lacticaseibacillus rhamnosus GG survival. While metabolic parameters remained unchanged, aguamiel syrup enhanced bioactive peptide production and antihypertensive activity (45.3%), suggesting its potential as a ...
Olvera‐Rosales Laura Berenice, Leonel‐Enríquez Jorge Eduardo, Pérez‐Escalante Emmanuel, Castañeda‐Ovando Araceli, Contreras‐López Elizabeth, Cruz‐Guerrero Alma Elizabeth, González‐Olivares Luis Guillermo   +6 more
wiley   +1 more source

[Montreal Cognitive Assessment (MoCA): normative data for Rosario metropolitan area population, Argentina]. [PDF]

Rev Neurol, 2022
Cervigni M, Martino P, Alfonso G, Politis D.   +3 more
europepmc   +1 more source

From Crisis to Resilience: Rethinking Urban Flooding and Groundwater Recharge in Bengaluru City, India

World Water Policy, Volume 12, Issue 3, August 2026.
ABSTRACT Bengaluru, a primary metropolitan centre in India, is currently grappling with the dual crises of urban flooding and severe groundwater depletion. These challenges are driven by rapid urbanization, which has seen built‐up areas increase from 42% to 86% over two decades, resulting in a dramatic loss of vegetation and wetlands.
S. Biswas, S. V. B. Patel, B. Maheshwari
wiley   +1 more source

Polarized effects of adenosine on blood–brain barrier integrity: Tightening from the luminal and opening from the abluminal side

British Journal of Pharmacology, Volume 183, Issue 16, Page 4761-4777, August 2026.
Background and Purpose Adenosine as a signalling molecule modifies blood–brain barrier (BBB) tightness in pathological conditions. Our aim was to investigate the direct and polarized effects of adenosine on the BBB using co‐culture and in vivo models. Experimental Approach The expression of adenosine receptors was measured by qRT‐PCR.
András Harazin, Gabriela Hurtado‐Alvarado, Lilla Barna, Arturo Contis‐Montes de Oca, Rocío Ruíz‐Manzano, Krisztián Laczi, András Kincses, Gergő Porkoláb, Gang Chen, Beatriz Gómez‐González, Mária A. Deli   +10 more
wiley   +1 more source