Results 121 to 130 of about 3,474,405 (252)

Coronavirus

open access: yes, 2020
En este recurso encontrará datos relevantes acerca del coronavirus, capítulo que fue realizado con el apoyo del doctor Camilo León del Centro Médico de la Fundación Universitaria del Área ...

core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Representaciones culturales: grupo llanera Areandina

open access: yes, 2020
1 archivo audiovisual ; 2:08 minutos.En este recurso los estudiantes y docentes de la Fundación Universitaria del Área Andina, realizan una demostración artística, con el fin de acompañar el viaje cultural virtual realizado por la ...

core  

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Tips para empezar bien la semana

open access: yes, 2019
Imagen ; 15 cm.En esta infografía el estudiante del Área Andina podrá encontrar tips o información acerca de como planear y empezar bien la ...

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NuPECC Survey on Experimental Nuclear Physics: Outlook for a Nuclear Physics Career in Europe

open access: yes
Nuclear Physics is considered as a very important community in Physics, particularly in Europe. However, this qualitative statement requires some quantitative backing. How many nuclear physicists are there in Europe? Where do they work? What do they work
Ramos, Inés Gómez   +1 more
core   +1 more source

Bienestar desde tu hogar: herramientas y prácticas para ser feliz

open access: yes, 2020
Archivo de audioEn esta entrega, Valentina Marín, asesora de felicidad para la rectoría nacional de la Fundación Universitaria del Área Andina brinda herramientas y prácticas para una vida feliz mientras se deba permanecer en ...

core  

Sentidos de nación y tecnociencia: una mirada comparativa en instituciones del área nuclear

open access: yesUniversitas Humanística, 2013
This paper provides an analysis of the links between national identity and technoscience. To do this, we will study the meanings of nation that are developed on two ceremonies commemorating the fiftieth anniversary of institutions dedicated to the ...
Ana Spivak L’Hoste, Matthieu Hubert
doaj  

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

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