Results 11 to 20 of about 720,537 (214)
Saúde & Tecnologia, 2015 Introduction – Single Photon Emission Computed Tomography synchronized with the electrocardiographic signal (Gated-SPECT) is central to the joint assessment of perfusion and left ventricular (LV) myocardial function. Objectives – Explore the relationship
Raquel Correia +2 more
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Influence of different parameters on the decrease of extra-myocardial activity Gated-SPECT studies
Saúde & Tecnologia, 2015 Introduction – Myocardial perfusion imaging (MPI) is one of the most indicated complementary diagnostic exams in cardiovascular disease. Extra myocardial activity is a recurrent problem in the acquisition and evaluation of functional image.
Andreia Rodrigues +4 more
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Saúde & Tecnologia, 2013 Introdução – A cintigrafia de perfusão do miocárdio (CPM) é um dos exames complementares de diagnóstico mais indicados na patologia cardiovascular. A atividade extramiocárdica é um problema recorrente na aquisição e avaliação da imagem.
Andreia Rodrigues +4 more
doaj +1 more source
Nuclear shapes are geometrically determined by the excess surface area of the nuclear lamina
Frontiers in Cell and Developmental Biology, 2023 Introduction: Nuclei have characteristic shapes dependent on cell type, which are critical for proper cell function, and nuclei lose their distinct shapes in multiple diseases including cancer, laminopathies, and progeria.
Richard B. Dickinson +3 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Saúde & Tecnologia, 2022 Introdução – A tomografia de emissão de fotão simples sincronizada com o sinal eletrocardiográfico (Gated-SPECT) é essencial para a avaliação conjunta da perfusão e da função ventricular esquerda (VE) do miocárdio.
Raquel Correia +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Factors that influence the stability of the FDG
Saúde & Tecnologia, 2015 Introduction – The absence of a cyclotron for production of 2-[18F]Fluor-2- -deoxy-D-glucose (18F-FDG) is now a reality for most of the centers where Positron Emission Tomography (TEP) exams are held in. It is therefore important to ensure the quality of
Ana Graça +4 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source