Results 71 to 80 of about 3,875 (160)

Évaluation de la prévalence des traumatismes en Gaule septentrionale pour le second âge du Fer

Bulletins et Mémoires de la Société d’Anthropologie de Paris, 2021
Frédéric Boursier, Jean-Gabriel Pariat, Raphaëlle Lefebvre, Anaïs Lebrun, Elodie Wermuth   +4 more
doaj   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, Volume 13, Issue 44, 7 August 2026.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Targeting the CTBP1–CETP axis overcomes ferroptosis resistance in non‐small cell lung cancer by altering lipid accumulation

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
CTBP1‐driven CETP activation orchestrates lipid accumulation to suppress MAPK‐dependent ferroptosis in non‐small cell lung cancer. Repurposing the clinical‐stage CETP inhibitor obicetrapib successfully overcomes this resistance in NSCLC patient‐derived organoids, highlighting a promising translational therapeutic strategy. Abstract Background Non‐small
Yanjie Chen, Heng Wang, Ximin Tan, Chenxi Yan, Fangfang Liu, Shuxuan Deng, Chengyan Wang, Yangchen Xia, Zhaolin Xu, Kongming Wu, Shanshan Huang, Qian Chu   +11 more
wiley   +1 more source

ATF4/SCO2 Inhibits Ferroptosis in Lung Cancer Through Activating the MAPK Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
ATF4 activates the transcription of SCO2 to increase SCO2 expression that further stimulates p38/ERK1 signals in MAPK pathway, ultimately promoting proliferation and migration while inhibiting apoptosis and ferroptosis of lung cancer cells. ABSTRACT Ferroptosis is a specific cell death form resulting from the iron‐dependent lipid peroxidation ...
Liang Yu, Sheng Zhang, Jinxi He, Bo Ma, Xuyang Song, Rui Qiu, Bo Yu   +6 more
wiley   +1 more source

Constitution et organisation d’un pôle d’occupation au premier âge du Fer dans la Plaine du Moulin à Vent à Cesson (Seine-et-Marne)

Revue Archéologique du Centre de la France, 2015
Located on the western board of the plateau Briard which dominates the valleys of the Seine and Yerres, there is the new town of Senart (77) on which an archaeological monitoring program has been systematical for nearly twenty years. In this article, the
Pierre Broutin, Éric Néré
doaj  

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu, Yi‐Fan Gu, Jian‐Qiao Li, Yi‐Heng Li, Yu‐Hu Chen, Lin‐Hui Wang, Zi‐Ru Wang, Yi‐Cong Wang, Min Yang   +8 more
wiley   +1 more source

Note complémentaire pour l’étude de l’occupation du cimetière du second Âge du Fer de Lailly Au-delà de l’eau (Yonne) : apports des archives de Michel Delinon

Revue Archéologique de l’Est
The aim of this note is to complete the data presented in the monograph on the excavations at the Lailly Au-delà de l’Eau cemetery published in this journal in 2020, by taking into account drawings of hitherto unknown objects.
Luc Baray
doaj   +1 more source

Museomic phylogenomics of Orthosiinae (Apocynaceae) integrating targeted sequencing and morphology

TAXON, Volume 75, Issue 4, August 2026.
Abstract Museum collections offer valuable resources for phylogenetic research, especially in taxonomically challenging groups. Here, we present a phylogenetic study of the South American Apocynaceae subtribe Orthosiinae, based on sequencing 835 nuclear genes and chloroplast genomes from ~120 species using a family‐specific probe set and multiple ...
Yam M. Pineda, Martha Kandziora, María Pinilla Vargas, Roswitha E. Schmickl, Ulrich Meve, Sigrid Liede‐Schumann, Nicolai M. Nürk   +6 more
wiley   +1 more source

The Natural Quassinoid Brusatol Enhances Venetoclax Efficacy and Overcomes Resistance in Myeloid Leukemias

Cancer Science, Volume 117, Issue 8, Page 2274-2288, August 2026.
Schematic illustration of the mechanisms by which the natural quassinoid brusatol induces apoptosis in myeloid leukemias and enhances venetoclax efficacy via p53‐dependent apoptosis and mitochondrial dysfunction. ABSTRACT While venetoclax‐based combinations have shown promising results in acute myeloid leukemia (AML), the remission duration is ...
Shin‐ichiro Kawaguchi, Kazuya Sato, Junko Izawa, Norihito Takayama, Hiroko Hayakawa, Ken Suzaki, Susumu Goyama, Chiyoko Kato, Eiji Sakashita, Kaoru Tominaga, Hitoshi Endo, Yoshinobu Kanda   +11 more
wiley   +1 more source

Pratiques funéraires des populations du second âge du Fer en Gaule : nouvelles perspectives de recherche et études préliminaires de cas champenois et normands

Bulletins et Mémoires de la Société d’Anthropologie de Paris
Recent methodological advances in archaeology, and preventive archaeology in particular, have prompted new interest in studies of Iron Age societies through their funerary practices.
Elodie Caserta, Lola Bonnabel, Gaëlle Granier   +2 more
doaj   +1 more source