Cancer Cytopathology, Volume 134, Issue 5, May 2026.ABSTRACT Background Current professional guidelines recommend discontinuing Papanicolaou (Pap) test screening in women aged 65 years and older who have had adequate prior negative testing. However, limited data exist on Pap test performance and histologic outcomes in this population.
Timothy G. Ramseyer +6 more
wiley +1 more source
Registry Study of the Working Group on Cervical Pathology and Colposcopy (AGCPC) on the Diagnostic Algorithm for the New Cervical Cancer Screening - Persistent HPV Infections and Squamous Cell Lesions: Evaluation of over 10000 Patients. [PDF]
Geburtshilfe FrauenheilkdHenes M +15 more
europepmc +1 more source
Decoding the Oncogenic Role of USP22 Through Pan‐Cancer Genomic and Epigenetic Analysis
Cancer Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background Ubiquitin‐specific protease 22, an important catalytic component of the human SAGA (Spt‐Ada‐GcN5 Acetyltransferase) complex, regulates the deubiquitination and methylation of histones, which in turn influences gene expression. Its overexpression alters gene regulation, transcription, cancer progression, and therapy resistance.
Uma Devi A., Prakash Kumar Shukla
wiley +1 more source
Joint nausea and fatigue profiles during chemotherapy identify patients with a higher symptom burden. [PDF]
Support Care CancerSingh KP +9 more
europepmc +1 more source
Indicators to identify cancer screening providers with suboptimal case detection: A scoping review
International Journal of Cancer, Volume 158, Issue 9, Page 2339-2358, 1 May 2026.What's new? Quality control of cancer screening programs is essential to maintaining high public health standards. Here, the authors reviewed monitoring of case detection in cervical and colorectal cancer screening programs in Europe, and evaluated its effectiveness. They analysed 20 different measures used for this purpose and showed that many of them
Jiayao Lei +5 more
wiley +1 more source
Multiomics Analysis Identifies Chromosomal Instability-Associated Immune-Related Signatures in Hepatocellular Carcinoma by Integrating Weighted Gene Coexpression Network Analysis (WGCNA) and Machine Learning. [PDF]
Hum MutatLi Z +5 more
europepmc +1 more source
Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.Cin‐FF's biocompatibility is concentration and formulation (gel or solution) dependent, showing varied effects on bacterial strains and cell lines. ABSTRACT This study evaluates cinnamoyl‐diphenylalanine dipeptide (Cin‐FF), a newly introduced gelator, for its antimicrobial efficacy, biocompatibility, and potential anticancer properties in solution and ...
Efstratios D. Sitsanidis +7 more
wiley +1 more source
MATLAB-candexch algorithm-enhanced UV spectrophotometric-chemometric models for green, blue, and white determination of cinnarizine, domperidone, and carcinogenic impurity in pharmaceuticals: NQS assessment and UN-SDGs integration. [PDF]
BMC ChemGhanem HN +4 more
europepmc +1 more source
Systemic Propagation of STING Signalling via Generation of Large Extracellular Vesicles
Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.ABSTRACT Large extracellular vesicles (EVs) derived from tumour cells play important roles in tumour formation and progression. However, it remains unclear why malignant cells produce these EVs and how they act in vivo. We employ a well‐characterized Drosophila tumour model and demonstrate that large EV biogenesis from malignant cells is an ...
Jiae Lee +3 more
wiley +1 more source
Chromosomal instability as a predictive biomarker for recurrence risk following transurethral resection of NMIBC. [PDF]
Front OncolDing Q +9 more
europepmc +1 more source