Results 31 to 40 of about 200,225 (332)
Les performances macroéconomiques inégalées du gouvernement de la RD. Congo de 2019 à 2022. Analyse critique [PDF]
Mouvements et Enjeux Sociaux, 2022 L’objectif de ce travail a consisté à démontrer objectivement les performances inégalées réalisées présentement dans le temps et/ou dans l’espace par le gouvernement congolais et les critiques y afférentes dont les solutions contribuent à l’amélioration ...
Constantin KASONGO MUNGANGA
doaj
Sustainability analysis of primary wastewater treatment by willow plantations in Québec
Environmental Research CommunicationsWastewater treatment is a necessary step to avoid environmental impacts of water consumption and usage. Traditional approaches are expensive and are limited to developed countries.
Noel Fagoaga +6 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Early Language Impairment as an Integral Part of the Cognitive Phenotype in Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Huntington's disease (HD) speech/language disorders have typically been attributed to motor and executive impairment due to striatal dysfunction. In‐depth study of linguistic skills and the role of extrastriatal structures in HD is scarce.
Arnau Puig‐Davi +13 more
wiley +1 more source
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
Synthèse de la Littérature et Structuration du Champ de Recherche en Économie et Finance Islamiques
Journal of Islamic EconomicsDepuis le début du XXIe siècle, on remarque une accélération significative de la recherche en économie et finance islamiques. Cette progression présente des défis en matière de compréhension des directions dans lesquelles la recherche se développe et d ...
Ezzedine Ghlamallah
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra +17 more
wiley +1 more source
Natures Sciences SociétésLe secteur du bâtiment et des travaux publics génère un impact très élevé sur l’environnement. Il contribue notamment au réchauffement climatique et à l’épuisement des ressources.
Blanquart Corinne +2 more
doaj +1 more source