Results 71 to 80 of about 1,748,485 (267)

Le recours aux affects ou une première réponse à la précarité du monde : 11-Septembre, canicule et tsunami [PDF]

open access: yes, 2006
La médiatisation de l'actualité est traversée par une tendance globale de proximité et de sollicitation des affects. Cette publicisation des émotions interroge de manière spécifique les fondements démocratiques de notre société, organisée autour d'une ...
Fragnon, Julien
core   +1 more source

Le genre homme-femme des auteurs et relecteurs de publications au Cirad (2014-2018) : état des lieux [PDF]

open access: yes, 2019
La présente étude vise à rendre compte de la participation par genre homme/femme des auteurs et des relecteurs Cirad, aux activités de publication scientifique et d'animation de revues (comités éditoriaux, comités de lecture, activités de reviewing) pour
Chirouze, Emilie   +3 more
core   +1 more source

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

open access: yesAdvanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang   +17 more
wiley   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu   +7 more
wiley   +1 more source

Magnetic and Crystal Symmetry Control on Spin Hall Conductivity in Altermagnets

open access: yesAdvanced Science, EarlyView.
Crystal structures and schematic illustrations of the spin Hall effect (SHE) in altermagnets. High‐symmetry RuO2 exhibits conventional SHE, while tilted RuO2 shows trivial unconventional SHE (USHE) caused by structural tilting. CrSb and MnTe, with reduced magnetic symmetry, display intrinsic USHE arising from symmetry‐driven spin–momentum locking ...
Dameul Jeong   +2 more
wiley   +1 more source

Meta‐GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility

open access: yesAdvanced Science, EarlyView.
This study incorporated 14 210 individuals to perform a GWAS meta‐analysis of six semen quality traits. The GWAS meta‐analysis identifies 234 GWAS loci associated with semen quality traits. The incorporation with a functional genomics resource explains potential genetic regulation of ∼40% GWAS signals underlying semen quality traits.
Qing Lin   +26 more
wiley   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

open access: yesAdvanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini   +24 more
wiley   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

open access: yesAdvanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy