Results 91 to 100 of about 53,485 (238)
Advanced Science, EarlyView.A universal hydrogel microparticle template with five DNA‐addressable domains decouples particle fabrication from barcode writing. Contact‐free multilaminar flow lithography produces >106 templates/h, and post‐fabrication domain‐selective hybridization converts one batch into large, user‐defined optical barcode libraries with robust decoding and re ...
Akihiro Eguchi +5 more
wiley +1 more source
Advanced Science, EarlyView.Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren +11 more
wiley +1 more source
TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains
Advanced Science, EarlyView.Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang +14 more
wiley +1 more source
Les élites d'origine maghrébine : l'arlésienne ?
, 1993 Wihtol de Wenden Catherine. Les élites d'origine maghrébine : l'arlésienne ?. In: Horizons Maghrébins - Le droit à la mémoire, N°20-21, 1993. Élites maghrébines de France. Politiques, associatives, religieuses, scientifiques, artistiques. pp.
Wihtol de Wenden, Catherine
core +1 more source
Advanced Science, EarlyView.Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo +11 more
wiley +1 more source
Mixed‐Valence Atomic‐Layer Iridium Patches Enhance Alkaline Hydrogen Evolution
Advanced Science, EarlyView.Engineering iridium architectures on Cu3P nanowires reveals that atomic‐layer Ir patches form a mixed‐valence interfacial motif with an anisotropic electronic structure. This configuration balances water dissociation and hydrogen adsorption/desorption, delivering superior alkaline hydrogen evolution with a 27 mV overpotential and 1 A cm−2 operation in ...
Payam Ahmadian Koudakan +7 more
wiley +1 more source
, 2016 Esto es lo que se pregunta esta obra, Elites: A General Model, de la mano de Murray Milner Jr., en un momento en el que las influencias sociales, los recursos económicos y las oportunidades políticas parecen estar, cada vez más, desigualmente ...
Juan Cartaya
core
Élites : origine, éducation, destination
International audienceQuelles sont les dynamiques de reproduction sociale des élites et comment les institutions d’enseignement les plus prestigieuses participent-elles à les entretenir ?
Pavie, Alice, Benveniste, Stéphane
core +1 more source
Advanced Science, EarlyView.This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou +4 more
wiley +1 more source
Cachacos y guaches: la plebe en los festejos bogotanos del 20 de julio de 1910
Anuario Colombiano de Historia Social y de la Cultura, 2011 El artículo se pregunta por la participación de los sectores populares en los festejos bogotanos del primer centenario de la Independencia colombiana. Desde un enfoque que puede definirse como de historia évènementielle o de corta duración, el objetivo ...
Alexander Pereira Fernández Pereira Fernández
doaj