Results 11 to 20 of about 283,415 (163)

Ethical dilemmas in infant mental health: Examples from child protection, home visiting, and medical contexts

open access: yesInfant Mental Health Journal: Infancy and Early Childhood, Volume 44, Issue 5, Page 614-624, September 2023., 2023
Abstract Infant mental health is explicitly relational and strengths based as a field. Ethical dilemmas in infant mental health have received insufficient attention at the level of infant mental health professionals (IMHP) and other professionals caring for infants who must grapple with questions of when caregivers and infants have conflicting ...
Charles H. Zeanah   +4 more
wiley   +1 more source

Chasing the Numinous: Hungry Ghosts in the Shadow of the Psychedelic Renaissance

open access: yesJournal of Analytical Psychology, Volume 68, Issue 4, Page 638-664, September 2023., 2023
Abstract In recent years a renewed scientific, public and commercial interest in psychedelic medicines can be observed across the globe. As research findings have been generally promising, there is hope for new treatment possibilities for a number of difficult‐to‐treat mental health concerns.
Helge Michael Osterhold   +1 more
wiley   +1 more source

Different modes of synaptic and extrasynaptic NMDA receptor alteration in the hippocampus of P301S tau transgenic mice

open access: yesBrain Pathology, Volume 33, Issue 1, January 2023., 2023
Differential alteration of synaptic versus extrasynaptic NMDARs in P301S mice. Reduced density of synaptic NMDARs in excitatory synapses in the hippocampus of P301S mice at 10 months. NMDARs at excitatory synapses established on pyramidal cell spines and interneurons are significantly reduced in the CA1 region of the hippocampus compared to age‐matched
Rocío Alfaro‐Ruiz   +8 more
wiley   +1 more source

Efficacy and Safety of an Ophthalmic DMPC‐Based Nanoemulsion in Patients with Dry Eye Disease: A Phase I/II Randomized Clinical Trial

open access: yesJournal of Ophthalmology, Volume 2023, Issue 1, 2023., 2023
Purpose. The goals of this study were to evaluate the safety and efficacy of an ophthalmic 1,2‐dimyristoyl‐sn‐glycero‐3‐phosphocholine (DMPC)‐based nanoemulsion (Nanodrop®) in patients with dry eye disease (DED). Methods. This was a randomized phase I/II multicentric, prospective, double‐blind clinical trial. Patients (phase I: n = 25 and phase II: n = 
Leopoldo M. Baiza-Durán   +4 more
wiley   +1 more source

Adrenal Vein Sampling in the Management of Primary Aldosteronism: The Added Value of Intraprocedural Cortisol Assessment

open access: yesInternational Journal of Endocrinology, Volume 2023, Issue 1, 2023., 2023
Introduction. Primary aldosteronism is the most common cause of secondary hypertension. Adrenal vein sampling is the gold standard for subtyping primary aldosteronism. However, this procedure is technically challenging and often has a low success rate.
Inês Manique   +13 more
wiley   +1 more source

How Did the COVID‐19 Lockdown Pandemic Affect the Depression Symptomatology in Mediterranean Older Adults with Metabolic Syndrome?

open access: yesDepression and Anxiety, Volume 2023, Issue 1, 2023., 2023
Background and Aims. To control the COVID‐19 spread, in March 2020, a forced home lockdown was established in Spain. In the present study, we aimed to assess the effect of mobility and social COVID‐19‐established restrictions on depressive symptomatology in older adults with metabolic syndrome.
Indira Paz-Graniel   +49 more
wiley   +1 more source

Severe Obesity in Women Can Lead to Worse Memory Function and Iron Dyshomeostasis Compared to Lower Grade Obesity

open access: yesInternational Journal of Endocrinology, Volume 2023, Issue 1, 2023., 2023
Objective. Obesity is one of the modifiable risk factors for dementia. Insulin resistance, the abundance of advanced glycated end‐products, and inflammation are some of the mechanisms associated with the lower cognitive performance observed in obesity.
Jessica M. V. Pino   +17 more
wiley   +1 more source

Helsinki in Zion: Hospital ethics committees and political gatekeeping in Israel/Palestine

open access: yesAmerican Anthropologist, Volume 124, Issue 4, Page 688-702, December 2022., 2022
Abstract This article looks at six months of the author's repeated attempts to obtain the approval of three Helsinki Committees (HCs, Israeli hospitals’ research ethics committees) to conduct ethnographic research with Palestinian physicians in Israeli hospitals.
Guy Shalev
wiley   +1 more source

Sutureless bioprosthesis for aortic valve replacement: Surgical and clinical outcomes

open access: yesJournal of Cardiac Surgery, Volume 37, Issue 12, Page 4774-4782, December 2022., 2022
Abstract Background Aortic valve stenosis is the most common adult valve disease in industrialized countries. The aging population and the increase in comorbidities urge the development of safer alternatives to the current surgical treatment. Sutureless bioprosthesis has shown promising results, especially in complex procedures and in patients ...
Ricardo Ferreira   +8 more
wiley   +1 more source

Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: a randomized phase II study of patients with previously untreated HER2-positive metastatic breast cancer. [PDF]

open access: yes, 2014
IntroductionThe purpose of this study was to retrospectively explore the relationship between human epidermal growth factor receptor 2 (HER2) messenger RNA (mRNA) expression and efficacy in patients receiving trastuzumab plus docetaxel (HT) or ...
Amler, Lukas C   +6 more
core   +3 more sources

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