Results 231 to 240 of about 4,539,801 (254)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Temporal Reproducibility of a Genetic Algorithm-Derived Health Risk Score: Standardized Out-of-Fold Validation Framework (2021-2023). [PDF]

JMIR Bioinform Biotechnol
Aoki Y, Takeda H, Yokota K, Yoshida R.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Effects of Food Characteristics on Masticatory and Swallowing Functions in Healthy Young Adults. [PDF]

J Texture Stud
Koide R, Ogawa T, Kanetaka H, Narihara T, Komine H, Tagaino R, Shigemitsu R, Shobara K, Hihara H, Yoda N.   +9 more
europepmc   +1 more source

Effectiveness Assessment of a Multi-Functional Neonatal Incubator in the NICU. [PDF]

Healthcare (Basel)
Choi H, Jang W.
europepmc   +1 more source

Improving Retrieval Augmented Generation for Health Care by Fine-Tuning Clinical Embedding Models: Development and Evaluation Study.

J Med Internet Res
Arzideh K, Schäfer H, Idrissi-Yaghir A, Schmidt CS, Eryilmaz B, Bahn M, Turki AT, Pollok OB, Hartmann EM, Winnekens P, Borys K, Haubold J, Nensa F, Hosch R.   +13 more
europepmc   +1 more source

AI-Generated Exercise Prescriptions for At-Risk Populations: Safety and Feasibility of a Large Language Model Assessed by Expert Evaluation. [PDF]

J Clin Med
Choi M, Park J, Lee M, Beom J, Jung SY, Lee K.   +5 more
europepmc   +1 more source

AI-assisted quantitative analysis for evaluating melanin distribution in 3D pigmented epidermis-on-a-chip models. [PDF]

Front Bioeng Biotechnol
Yao Y, Du X, Li Y, Ma Y, Li Y, Zhang Z, Song B, Li X, Zhang J, Ouyang J, Si N, Yin N, Han Q, Gu Z, Chen Z.   +14 more
europepmc   +1 more source

Evaluating the Combined Effects of an Adverse Childhood Experiences-Focused Family Advocate Model and the Strengthening Families Program: Study Protocol for a Hybrid Type 1 Effectiveness-Implementation Trial in 36 New Jersey Communities.

JMIR Res Protoc
Elgin D, Graham PW, Johnson K, Khan S, Mills M, Wondimagegnehu F, Gibbons B, Williams J, Jiang X, Zapcic A, Simon B.   +10 more
europepmc   +1 more source

Number Needed to Teach (N2T2): Bringing Additional Context to the Evaluation of CME Outcomes. [PDF]

J CME
Dietze DT.
europepmc   +1 more source