Results 51 to 60 of about 4,513 (147)

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

ТранÑпериотонеална радикална нефректомија во третманот на карциномот на бубрег: компликации [PDF]

open access: yes, 2016
Ðаnравен е преглед на наашето хируршко иÑкуÑтво Ñо интра и поÑтоnеративните компликации, документирано кај 275 паци­ÐµÐ½Ñ‚и Ñо карциноми на бубрег
ПетровÑки, Д   +1 more
core  

Voltage‐Driven Non‐Volatile Interconversion Between Giant Single‐Domain and Multidomain Magnetic States in a Multiferroic Heterostructure

open access: yesAdvanced Science, EarlyView.
Non‐volatile voltage control of magnetic configurations is achieved in a strain‐coupled multiferroic heterostructure. Voltage pulses reversibly interconvert giant single‐domain and multidomain magnetic states, which remain stable at zero applied voltage. ABSTRACT Voltage control of magnetic states in multiferroic heterostructures represents a promising
M. Ghidini   +11 more
wiley   +1 more source

Kлинички тек и иÑход кај пациенти Ñо рано дијагноÑтицирани конгенитални малформации на бубрезите и уринарниот тракт [PDF]

open access: yes, 2018
Congenital anomalies of the kidney and urinary tract- CAKUT are common childhood pathology accounting for 20-30% of all perinatally detected congenital anomalies. The importance of CAKUT is the risk they represent to kidney function deterioration and end-
ПапазовÑка-ЧерепналковÑки (Papazovska-Cherepnalkovski), Ðнет (Anet)   +6 more
core  

A Reconfigurable Memristive Spiking Neuron Enabling Advanced Neuromorphic Computing

open access: yesAdvanced Science, EarlyView.
Pek Jun Tiw and co‐workers develop a reconfigurable memristive neuron that can exhibit four spiking behaviors with freely tunable spike train parameters. The neuron supports multiplexed spike encoding of multiple pieces of information. It also supports advanced neural network strategies, such as neural heterogeneity and dynamic mode switching ...
Pek Jun Tiw   +6 more
wiley   +1 more source

ОÑврт на два Ñлучаја муковиÑцидоза (Fibrosis Cystica) кај новородено

open access: yes, 2017
Two sucker babies with fibrosa cystic have been presented: in one of them the disease was severe with the lethal outcome, while the other baby could be successfully treated.
СпировÑки (Spirovski), Зоран (Zoran)   +2 more
core  

Инциденција и преваленција на тироиден карцином во Република Маке- донија (1999-2010) [PDF]

open access: yes, 2017
Epidemiological data indicates that  thyroid carcinoma (TC)  is the most frequent endocrinological tumors, participating with around 1%  from all malignomas.
Маказлиева (Makazlieva), Тања (Tanja)   +3 more
core  

Photoactivation‐Enabled Tunable Room‐Temperature Phosphorescence and Thermally Activated Delayed Fluorescence in Crystalline Materials

open access: yesAdvanced Science, EarlyView.
This work is the first to demonstrate the regulation of photoactivated room‐temperature phosphorescence (RTP) and thermally activated delayed fluorescence (TADF) in crystalline materials without any pretreatment. Furthermore, we reveal the underlying mechanisms by uncovering the role of host‐guest energy level alignment, exciton lifetime, crystallinity,
Lisha Zhang   +5 more
wiley   +1 more source

МУЛТИМЕДИСКИ СИСТЕМИ [PDF]

open access: yes, 2016
изваР...
Салиу, Ðрменд
core  

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

open access: yesAdvanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

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