Results 131 to 140 of about 6,172,220 (242)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

СамоубиÑтвата во Скопје и околината во текот на 1979 година

open access: yes, 2017
The aim of our examination was to establish the number of suicides, oldness, sex, professions, calendar and meteorological time, place, manner and means of execution. Our basic duty was to analyse this phenomenon, which number rise slowly, from the year (
Тарник-Митрева (Tarnik-Mitreva), Љерка (Ljerka)   +2 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Причини и поÑледици на повредите на градниот кош во мирновременÑки и воени уÑлови

open access: yes, 2017
We had 107 patients with chest injuries – 95 of them were blunt wounds and 12 were wounds from weapons (rifles, revolvers, shotguns, knives, bayonets ...).Chest injuries are, as serious in the peaceful-time, as in the military conditions. They bring into
Сарач (Sarach), Бранка (Branka)   +2 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

ИÑкуÑÑтво, показ, влаÑть. Фелипе IV и иконографичеÑÐºÐ°Ñ Ð¿Ñ€Ð¾Ð³Ñ€Ð°Ð¼Ð¼Ð° Зала ЦарÑтва дворца БуÑн-Ретиро. ÐтлантичеÑкий контекÑÑ‚

open access: yes, 2019
The Palace of the Buen Retiro was constructed between 1630 and 1635 in the suburbs of Madrid as place of rest for Philip IV and his court. One of its main rooms was called Salon de Reinos, a place that hosted an iconographic program that, besides the ...
García Sánchez , Laura
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Чемамюлл: ÑвÑÑ‰ÐµÐ½Ð½Ð°Ñ Ñ‚Ñ€Ð°Ð´Ð¸Ñ†Ð¸Ñ Ð²Ñ‹Ð¶Ð¸Ð²Ð°Ð½Ð¸Ðµ и Ñимвол культурного ÑÐ¾Ð¿Ñ€Ð¾Ñ‚Ð¸Ð²Ð»ÐµÐ½Ð¸Ñ Ð¼Ð°Ð¿ÑƒÑ‡Ðµ

open access: yes, 2019
This essay presents preliminary results of an ethnographic and descriptive research on the Mapuche statuary known as chemamüll together with the first record on its identification and its current territorial dispersio in the Araucania Region.
Saavedra, José, Salas Olave, Eugenio
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Razeyev D. N. I. Kant's teleology [PDF]

open access: yesКантовский сборник, 2011
Balanovsky, V. V.
doaj   +1 more source

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