Results 111 to 120 of about 6,151,641 (285)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Razeyev D. N. I. Kant's teleology [PDF]

Кантовский сборник, 2011
Balanovsky, V. V.
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Characterizing N-type derivations on standard operator algebras by local actions

AIMS Mathematics
On an infinite dimensional complex Hilbert space $ \mathcal{H} $, we consider a standard operator algebra $ \mathcal{S} $ with an identity operator $ I $ that is closed with respect to adjoint operation.
Khalil Hadi Hakami , Junaid Nisar , Kholood Alnefaie , Moin A. Ansari   +3 more
doaj   +1 more source

ÐзмеÑиÑелÑÐ½Ð°Ñ ÑиÑÑема Ð´Ð»Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° и мониÑоÑинга ÑÑемоÑа

, 2016
Семён Алексеевич Котляров
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

ÐÑÑледование возможноÑÑи ÑÑÐ¸Ð»ÐµÐ½Ð¸Ñ ÑоÑоÑока в геÑеÑоÑÑÑÑкÑÑÑÐ°Ñ II - Ñипа на оÑнове ÑзкозоннÑÑ Ð¿Ð¾Ð»ÑпÑоводников Ð3Ð5

, 2017
Андрей Юрьевич Глотов
openalex   +1 more source

Влијаниа на Ñпортувањето врз некои функционални параметри кај Ñтудентите

, 2017
It was interesting to examine how the sport impresses at functional (motorial) characteristics of students.About that intention there were examined, 2306 students of whom 1232 girls and 1076 boys, with the age of 14-18 years.There were examined the ...
СтолевÑки (Stolevski), Владо (Vlado), Тројачанец (Trojachanec), Здравко (Zdravko)   +1 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

СиÑÑема пожаÑной Ð¾Ñ ÑÐ°Ð½Ñ Ð¿ÑедпÑиÑÑиÑ

, 2017
Георгий Константинович Яшин
openalex   +1 more source