Effect of Vitamin D Supplementation on Cardiometabolic Outcomes in Older Australian Adults-Results from the Randomized Controlled D-Health Trial. [PDF]
Duarte Romero BL +16 more
europepmc +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Effectiveness of Guided Internet-Based Cognitive Behavioral Therapy for Adult Anxiety and Depression in Routine Care: An Observational Study. [PDF]
Jensen EK +3 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Multivitamin supplements are not superior to nutrition education in improving fat-soluble vitamin levels: A double-blind randomized controlled trial. [PDF]
Yusupu S +7 more
europepmc +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Formal Synthesis of <i>Ortho</i>-Cyanated <i>N</i>-Heterocycles via Direct, Metal-Free Cyanation of <i>N</i>-Oxides Under Benign Conditions. [PDF]
Xiao H, Wufuer R, Wang D.
europepmc +1 more source

