Results 211 to 220 of about 6,151,641 (285)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Serum 25-Hydroxyvitamin D Levels in Breast Cancer Patients: A Cross-Sectional Analysis by Molecular Tumor Subtypes. [PDF]

J Clin Med
Weber D, Stanisławek A, Irzmańska-Hudziak A, Kulik T, Pacian AB, Baryła-Matejczuk M, Łuczyk M, Łuczyk R.   +7 more
europepmc   +1 more source

ÐÑÑледование влиÑÐ½Ð¸Ñ ÑÑÑÑкÑÑÑÑ Ð¸Ð½Ð²ÐµÑÑиÑионного поÑÑÑÐµÐ»Ñ Ð½ÐµÐ³Ð¾ÑÑдаÑÑÑвеннÑÑ Ð¿ÐµÐ½ÑионнÑÑ Ñондов по обÑзаÑелÑÐ½Ð¾Ð¼Ñ Ð¿ÐµÐ½ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¼Ñ ÑÑÑÐ°Ñ Ð¾Ð²Ð°Ð½Ð¸Ñ Ð½Ð° Ð´Ð¾Ñ Ð¾Ð´Ð½Ð¾ÑÑÑ Ð¸Ð½Ð²ÐµÑÑиÑий

, 2016
Наталья Игоревна Белясова
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Progressive Changes in Brain Morphology in People With Idiopathic Generalized Epilepsy. [PDF]

Neurology
Xiao F, Zhang Y, Wandschneider B, Binding LP, Giampiccolo D, Fleury M, Delazer L, Pimentel BC, Puntambekar I, Fukuma K, Caciagli L, Sander JW, Duncan JS, Zhou D, Koepp MJ.   +14 more
europepmc   +1 more source

ХХV ÐÑжнаÑÐ¾Ð´Ð½Ð°Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð²Ð°Ñ ÐºÐ°Ð½ÑеÑÑнÑÑÑ âÐелаÑÑÑка-полÑÑкÑÑ Ð¼Ð¾ÑнÑÑ, лÑÑаÑаÑÑÑнÑÑ, гÑÑÑаÑÑÑнÑÑ Ñ ÐºÑлÑÑÑÑнÑÑ ÑÑвÑзÑâ: Ñ Ð³Ð¾Ð½Ð°Ñ Ð¿ÑаÑеÑаÑа ÐлÑжбеÑÑ CмÑлковай

, 2016
Maryna Swistunowa
openalex   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

ÐÐРÐÐÐЯÐÐЯ ÐФÐÐТÐÐÐÐСТРСТÐÐÐÐРТÐÐÐ¥ ТРÐÐÐÐРÐЧÐÐÐ¥ РÐÐÐÐÐРХÐÐÐÐТÐРÐÐÐÐ ÐÐЯ 4-Ñ ÐÐÐÐÐЧÐÐÐ ÐÐТÐÐÐРÐÐ ÐÐЦÐÐÐТÐÐ Ð ÐÐСÐÐÐРРÐÐÐÐÐÐ ÐУÐЬТÐРÐÐÐСТÐÐТÐÐÐРТУÐÐРÐУÐЬÐÐУ

, 2013
Н.А. Литвиненко, С.О. Черенько, Л.М. Циганкова, Я.В. Вольський, О.Р. Тарасенко   +4 more
openalex   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source