Results 211 to 220 of about 5,597,410 (239)

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Vitamin D-related risk factors for preterm and full-term infants at birth: a retrospective study. [PDF]

BMC Pediatr
Wu M, Zhao M, Jin X, Zhang Y, Zheng X, Xiao X.   +5 more
europepmc   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Elevated Fcy receptor expression augments pro-inflammatory macrophage phagocytosis in systemic sclerosis and associated rheumatic diseases. [PDF]

Rheumatology (Oxford)
Hukara A, Bonazza GA, Tabib T, Micheroli R, Jordan S, Bürki K, Rudnik M, Ciurea A, Distler O, Lafyatis R, Błyszczuk P, Kania G.   +11 more
europepmc   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Current Practice in the Measurement and Management of Vitamin D Status in Elite Sport and Parasport. [PDF]

Eur J Sport Sci
Owens DJ, Kasper AM, Close GL.
europepmc   +1 more source

Efficacy, Safety, and Cost-Effectiveness of N-Acetylcysteine in Preventing Amphotericin B Nephrotoxicity in Egyptian Patients with Hematological Malignancies: A Randomized Controlled Trial. [PDF]

Hosp Pharm
Ebid AIM, Mohamed HS, Mohammed YMM, Mohamed Abdel Motaleb SM.   +3 more
europepmc   +1 more source

Sex-based variations in the nutritional and functional status of hemodialysis patients in Palestine: a cross-sectional study. [PDF]

BMC Nutr
Hamdan Z, Nazzal Z, Zidan S, Bsharat L, Ishtayah S, Sammoudi S, Badrasawi M.   +6 more
europepmc   +1 more source

Iron metabolism disorder and artesunate inhibiting tumor growth by inducing ferroptosis in Lymphangioleiomyomatosis. [PDF]

Respir Res
Bai W, Zhang S, Hua L, Wang D, Guo M, Wang X, Zhou Y, Cao Y, Wang Q, Zhang N, Xue B, Xie M.   +11 more
europepmc   +1 more source