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, 2018
Non-communicable diseases, also known as modern-life diseases, are the leading cause of morbidity and mortality in the world and in the Republic of Macedonia. The complexity of their occurrence, often associated with multifactorial etiology and lifestyle
Ð¡Ð¿Ð°ÑÐ¾Ð²ÑÐºÐ¸ (Spasovski), ÐœÐ¾Ð¼Ðµ (Mome) +3 more
core +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source

ÐÐÐ¢Ð˜ÐœÐ˜ÐšÐ ÐžÐ‘ÐÐ Ð Ð•Ð—Ð˜Ð¡Ð¢Ð•ÐÐ¦Ð˜ÐˆÐ (ÐÐœÐ ) Ð’Ðž Ð•Ð’Ð ÐžÐŸÐ Ð˜ Ð‘ÐÐ›ÐšÐÐÐ¡ÐšÐ˜ÐžÐ¢ Ð Ð•Ð“Ð˜ÐžÐ – ÐŸÐ Ð•Ð“Ð›Ð•Ð” ÐÐ Ð¡Ð•Ð“ÐÐ¨ÐÐÐ¢Ð Ð¡ÐžÐ¡Ð¢ÐžÐˆÐ‘Ð [PDF]

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source

N-[4-(β-d-Allopyranosyloxy)benzylidene]methylamine

Acta Crystallographica Section E, 2009
The title compound, C14H19NO6, was synthesized by the condensation reaction between hecilid (4-formylphenl-β-d-allopyranoside) and methylamine in methanol.
Shu-Fan Yin +4 more
doaj +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source

Degree sequence for k-arc strongly connected multiple digraphs

Journal of Inequalities and Applications, 2017
Let D be a digraph on { v 1 , … , v n } $\{v_{1},\ldots, v_{n}\}$ . Then the sequence { ( d + ( v 1 ) , d − ( v 1 ) ) , … , ( d + ( v n ) , d − ( v n ) ) } $\{ (d^{+}(v_{1}), d^{-}(v_{1})), \ldots, (d^{+}(v_{n}), d^{-}(v_{n}))\}$ is called the degree ...
Yanmei Hong, Qinghai Liu
doaj +1 more source

Forest Gothic of D. N. Mamin-Sibiryak

Филологический класс, 2023
The article analyzes a micro detail of D. N. Mamin-Sibiryak’s landscape poetics: the metaphorical epithet Gothic in descriptions of coniferous forests of the Urals, its semantic role, and genesis.
doaj +1 more source

Improving the Gilbert-Varshamov bound for $q$-ary codes [PDF]

Discrete Mathematics & Theoretical Computer Science, 2005
Given positive integers $q$, $n$ and $d$, denote by $A_q(n,d)$ the maximum size of a $q$-ary code of length $n$ and minimum distance $d$. The famous Gilbert-Varshamov bound asserts that $A_q(n,d+1) \geq q^n / V_q(n,d)$, where $V_q(n,d)=\sum_{i=0}^d ...
Van H. Vu, Lei Wu
doaj +1 more source

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