Results 81 to 90 of about 5,597,410 (239)

Влијаниа на Ñпортувањето врз некои функционални параметри кај Ñтудентите

, 2017
It was interesting to examine how the sport impresses at functional (motorial) characteristics of students.About that intention there were examined, 2306 students of whom 1232 girls and 1076 boys, with the age of 14-18 years.There were examined the ...
СтолевÑки (Stolevski), Владо (Vlado), Тројачанец (Trojachanec), Здравко (Zdravko)   +1 more
core  

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

СолдатÑкие жены в XVIII – начале XX в.: опыт реконÑтрукции Ñоциального ÑтатуÑа,

, 2006
Pavel P. Shcherbinin
openalex   +1 more source

Тенденции в Ð¿Ñ€Ð¾Ð¸Ð·Ð²Ð¾Ð´Ð¸Ñ‚ÐµÐ»Ð½Ð¾Ñ Ñ‚Ñ‚Ð° на труда в Ð±ÑŠÐ»Ð³Ð°Ñ€Ñ ÐºÐ°Ñ‚Ð° минна Ð¸Ð½Ð´ÑƒÑ Ñ‚Ñ€Ð¸Ñ [PDF]

, 2020
Ð’Ðμñ Ðμð Ð ̧Ð ⁄ Ðœð ̧Ñ‚Ðμð
openalex  

ÐšÐ»Ð¸Ñ€ÐµÐ½Ñ Ð½Ð° I-131 и Ts-99 во тиреоидеа кај Ñтаорец

, 2017
Thyroid clearance of J-131 and Tc-99m after simultaneous subcutaneous injection in rats were estimated in the early phase. Arterial blood samples were drawn with a polyethene catheter inserted in the iliac artery in intervals of two minutes.
Таџер (Tadzher), ИÑак (Isak), ГеоргиевÑки (Georgievski), Славко (Slavko)   +1 more
core  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Проценка на ризик за безбедноÑта на водата за пиење и водоÑнабдувањето во КичевÑкиот регион за периодот од 1996-2013 година

, 2017
Intensification of systemic chemotherapy with in- clusion of high doses methotrexate (MTX) has contributed to the improvement of event-free survival in children with acute lymphoblastic leukemia (ALL). Despite this benefit, this agent might cause serious
ЕфтимијадоÑка (Eftimijadoska), Фани (Fani)
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source