Results 71 to 80 of about 109 (108)

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

Serrodyne‐Enabled Dual Electro‐Optic Comb Interferometry for High‐Precision Absolute Ranging and Integration‐Ready Metrology

Advanced Science, EarlyView.
A serrodyne‐modulated dual electro‐optic comb interferometer is presented that achieves sub‐nanometer precision in absolute distance measurements. The system also supports diverse applications such as depth imaging and vibration sensing. With features of low RF power, wide frequency‐shifting range, and full integration potential, the system offers a ...
Xiaoyang Guo, Xusheng Yang, Jiawen Zhi, Chenggang Shao, Hanzhong Wu   +4 more
wiley   +1 more source

3D Topological Inorganic Electrides: Screening, Properties, and Applications

Advanced Science, EarlyView.
In inorganic electrides, zero‐, one‐, and two‐dimensional (0D, 1D, and 2D) interstitial anionic electrons interconnect within lattice cavities, collectively forming a three‐dimensional (3D) network, further coupling magnetism and topological features, leading to the emergence of 3D topological inorganic electrides.
Zhenzhou Guo, Weizhen Meng, Qianwen Zhang, Xia Cheng, Shiyao Wang, Yalong Jiao, Xiaoming Zhang, Ying Liu, Tie Yang   +8 more
wiley   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

CsPbBr3 Perovskite‐Based Heterostructures in Photocatalysis: Mechanisms, Stability, and Multifunctional Performance

Advanced Science, EarlyView.
This review synthesizes breakthroughs in CsPbBr3 heterostructure photocatalysis: 1) Mechanistic insights on band alignment engineering (Type‐II/Z/S‐scheme) for suppressed charge recombination; 2) Stabilization strategies via interfacial encapsulation and defect passivation overcoming hydrolysis; 3) Multifunctional design principles enabling efficient ...
Kuanxin Lv, Zhenzhen Li, Xing Huang, Zetong Cheng, Zhongyan Wang, Hang Zhao   +5 more
wiley   +1 more source

Targeting Seipin to Alleviate Hepatic Steatosis in Zebrafish (Danio Rerio)

Advanced Science, EarlyView.
Seipin plays a crucial role in lipid metabolism. Seipin overexpression ameliorates high‐fat‐diet‐induced hepatic steatosis and enhances growth in zebrafish. Mechanistically, Seipin interacts with Plin2 to promote Plin2 degradation and enhances phosphatidylcholine synthesis via Seipin/CCTα/CHPT interactions.
Weijia Li, Yanan Shen, Zengqi Zhao, Baolin Li, Shunlang Wen, Rui Zhan, Qinghui Ai   +6 more
wiley   +1 more source

Mussel‐Inspired Self‐Assembly of PtO4 Atomic Catalysts for Interfacial Synergistic Hydrogen Evolution

Advanced Science, EarlyView.
Mussel‐inspired strategy for self‐assembling PtO4 atomic catalysts on different 2D substrates is presented. Notably, the self‐assembled PtO4 site exhibits up to a 30‐fold enhancement of mass activity compared to commercial Pt/C catalysts, contingent upon the choice of substrate material.
Yeo Hoon Yoon, Karthikeyan Jeyakumar, Gang San Lee, Jayaraman Balamurugan, Suchithra Padmajan Sasikala, Chan Woo Lee, Colin Wing‐Lok Cheng, Jun Beom Kim, Haeshin Lee, Sang Ouk Kim   +9 more
wiley   +1 more source

Unveiling Charge Transfer and Recombination Dynamics in 3D/2D Heterostructure via Ultrafast Spectroscopy for Efficient Perovskite Solar Cells

Advanced Science, EarlyView.
Charge transfer and recombination dynamics at 3D/2D perovskite heterostructure have been fully investigated via combined state‐of‐the‐art ultrafast spectroscopies, aiding to design of the desired 3D/2D perovskite heterostructure and thus push 3D/2D perovskite solar cell technology forward.
Di Li, Junhan Xie, Shaobing Xiong, Xiaoxiao Zang, Zhennan Lin, Yuning Wu, Weimin Liu, Bo Li, Zhenrong Sun, Junhao Chu, Qinye Bao   +10 more
wiley   +1 more source

Twist Grain Boundary Phases in Proper Ferroelectric Liquid Crystals Realm

Advanced Science, EarlyView.
A new type of twist‐grain‐boundary (TGB) phases, with a periodic, helical arrangement of ferroelectric smectic blocks, are reported, formed by molecules with giant longitudinal dipole moment. They emerge below the antiferroelectric smectic phase, and their structure is governed by electrostatic interactions amplified by weak chiral forces.
Damian Pociecha, Jadwiga Szydlowska, Nataša Vaupotič, Katarzyna Kwiatkowska, Marijus Juodka, Julian Spiess, John MD Storey, Corrie T. Imrie, Rebecca Walker, Ewa Gorecka   +9 more
wiley   +1 more source

Dynamic Synthesis of Multi‐Modal Representations for CITE‐seq Data Integration and Analysis

Advanced Science, EarlyView.
The accurate integration of CITE‐seq modalities faces challenges due to complex RNA‐protein nonlinear interactions and computational inefficiencies. A lightweight framework that adaptively fuses RNA and ADT modalities, and refines them through fine‐grained learning is developed to address this issue.
Yinan Shi, Yanchi Su, Yue Cheng, Ka‐Chun Wong, Yunhe Wang, Xiangtao Li   +5 more
wiley   +1 more source