Results 231 to 240 of about 6,284,543 (247)

2<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidin-4-amine derivatives as novel selective fibroblast growth factor receptor 2 (FGFR2) inhibitors. [PDF]

J Enzyme Inhib Med Chem
Wu P, Tian Z, Shen W, Xun Q, Tian Y, Li H, Yang B, Chang S, Huang W, Wang Z, Ding K, Ma D.   +11 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Safety of intravenous neridronate in pediatric patients: insights from the monocentric retrospective NAPOLEON cohort. [PDF]

Ther Adv Musculoskelet Dis
Costi S, Amati A, Di Taranto R, Baldo F, Crotti C, Ricci M, Giani T, Gattinara MV, Varenna M, Caporali R, Chighizola CB, Marino A.   +11 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Pediatric ureteral stenting: state-of-the-art review. [PDF]

World J Urol
Altunhan A, Soyturk S, Herrmann TRW, Gauhar V, Tokas T, Sultan S, Bujons A, Silay MS, Somani BK, Guven S.   +9 more
europepmc   +1 more source

Optimization of systemic AAV9 gene therapy in Niemann-Pick disease, type C1 mice. [PDF]

Life Sci Alliance
Mylvara AV, Gibson AL, Gu T, Davidson CD, Incao AA, Melnyk K, Gembic SR, Pierre-Jacques D, Cologna SM, Venditti CP, Porter FD, Pavan WJ.   +11 more
europepmc   +1 more source

Validation of an enhanced pediatric vitamin D deficiency score incorporating sun exposure timing and BMI z-score: analysis in a combined cohort of children. [PDF]

Eur J Pediatr
Calcaterra V, Cena H, Biino G, Scavone IAM, Vincenti A, Zuccotti G.   +5 more
europepmc   +1 more source