Results 91 to 100 of about 121 (121)

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

Epilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing, Lirong Han, Dongjun Guo, Thomas J. Foutz, Michael Wong   +4 more
wiley   +1 more source

Intracranial electroencephalographic connectivity analysis to localize epileptogenic networks: Systematic review and meta‐analysis from ILAE Epilepsy Surgery Networks Task Force

Epilepsia, EarlyView.
Abstract Intracranial electroencephalographic (iEEG) connectivity analysis is a promising method to localize epileptic networks and guide surgical planning in focal drug‐resistant epilepsy. Despite numerous studies exploring its utility, the added value of iEEG connectivity over standard clinical presurgical evaluation remains unclear.
Nishant Sinha, Daniel J. Zhou, Victoria L. Morgan, Dario J. Englot, Leonardo Bonilha, Milan Brázdil, Xiaosong He, Riki Masumoto, Quy Cao, Terence J. O'Brien, Chengyuan Wu, Erik Kaestner, Carrie McDonald, Ezequiel Gleichgerrcht, Aileen McGonigal, Kathryn A. Davis   +15 more
wiley   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Recent advances in organic broad‐spectrum photodetection materials and devices

InfoMat, EarlyView.
Graphical Abstract This review systematically outlines the evolution of organic photodetectors from fullerene‐based to advanced non‐fullerene acceptors, highlighting how molecular engineering (e.g., D–A, quinoidal, and A‐D‐A′‐D‐A architectures) extends spectral response into the short‐wave infrared region.
Yilin Zhao, Shijia Tan, Deyang Ji, Wenping Hu   +3 more
wiley   +1 more source

Reassessing the Cross‐Sectional Fiscal Multiplier: Evidence From U.S. Defense Procurement, 1966–2019

Journal of Applied Econometrics, EarlyView.
ABSTRACT This paper revisits the empirical analysis of Nakamura and Steinsson (2014). I reconstructed and extended the original dataset to cover the period 1966–2019, harmonizing two major sources of data: the Defense Contract Action Data System (DCADS) and USAspending.gov. I discuss how to aggregate these contract‐level data to better capture spending
Gianluca Pallante
wiley   +1 more source

The role of harms and burdens in clinical practice guidelines: Lessons learned from the American Psychological Association's guideline development

Clinical Psychology: Science and Practice, EarlyView., 2020
Abstract Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options.
Raquel W. Halfond, Caroline Vaile Wright, Lynn F. Bufka   +2 more
wiley   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro, Rosângela Mayer Gonçalves, Marcelle Gomes Pegurier, Isabelle Amorim, Alexandre Malta Rossi, Leandra Santos Baptista   +5 more
wiley   +1 more source

A Power‐Efficient Monte Carlo Framework for Nonlinear Light–Matter Interactions: In Silico Modeling of Spontaneous and Stimulated Raman Scattering in Turbid Media

Journal of Raman Spectroscopy, EarlyView.
Power‐efficient Monte Carlo modeling of nonlinear light–matter interactions in turbid media is demonstrated using Apple Silicon–accelerated photon transport. The Metal‐base framework enables accurate simulation of spontaneous and stimulated Raman scattering, revealing detection‐dependent SRS efficiency while providing a scalable, energy‐efficient ...
Ilya Vladyko, Vladislav Yakovlev, Alexander Doronin   +2 more
wiley   +1 more source

Comparing treatment outcomes of prolonged exposure therapy across trauma type and veteran status

Journal of Traumatic Stress, EarlyView.
Abstract This retrospective cohort study evaluated the effectiveness of prolonged exposure therapy (PE) across trauma types (combat, terror, civilian) and veteran status (military veterans vs. civilians) in a real‐world clinical setting. We hypothesized that individuals who experienced combat‐ and terror‐related trauma would have higher baseline ...
Nitsa Nacasch, Roy Aloni, Chen Avni, Lilach Rachamim, Edna Foa, Paz Toren   +5 more
wiley   +1 more source

Efficient First‐Principles Inverse Design of Nanolasers

Laser &Photonics Reviews, EarlyView.
This article introduces a first‐principles inverse‐design framework for nanolasers that directly incorporates nonlinear lasing physics. By unifying steady‐state ab‐initio laser theory (SALT) with topology optimization, it reveals how spatial hole burning, gain saturation, and cavity‐emitter coupling shape laser performance, enabling efficient discovery
Beñat Martinez de Aguirre Jokisch, Alexander Cerjan, Rasmus Ellebæk Christiansen, Jesper Mørk, Ole Sigmund, Steven G. Johnson   +5 more
wiley   +1 more source