Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source
Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: in vivo kinetic characterization of 2,3-bisphosphoglycerate synthase/phosphatase using 13C and 31P NMR. [PDF]
Mulquiney PJ, Bubb WA, Kuchel PW.
europepmc +1 more source
Aqueously Upcycled Lignin with Emergent Tribonegativity for Skin‐Integrated Triboelectronics
Aqueously upcycled lignin is transformed into a printable ink that self‐assembles into a nanotextured surface during printing with the highest reported biopolymer‐based tribonegativity. The resulting skin‐integrated triboelectric sensor enables high‐fidelity cardiovascular monitoring and objective mental workload classification, demonstrating a ...
Robert Ccorahua‐Santo +3 more
wiley +1 more source
Phase‐Change Solvents for Thermally Switchable Ion Conduction in Organogels
Organogels containing salts dissolved in phase‐change solvents exhibit thermally switchable ion conduction. The organogels, which display an over 10 000‐fold on‐off ratio and high cycling stability, can be synthesized with a wide range of salts and customizable conductivity/temperature relations for applications in ionotronics and energy storage ...
Yi‐ming Yuan, Thomas B. H. Schroeder
wiley +1 more source
Using femtosecond ablation, we show that an ordered, stoichiometric crystalline PdSe2 target can be controllably converted into a stable, disordered, non‐stoichiometric, and highly functional amorphous nanomaterial, PdSe2−x${\rm PdSe}_{2-x}$. The obtained nanoparticles offer significant advantages over conventional planar plasmon‐free substrates due to
Andrei Ushkov +18 more
wiley +1 more source
Development of Laterally Graded X‐Ray Multilayer Optics
This work presents the development of laterally graded X‐ray multilayer optics with both constant and variable lateral gradients. By precisely controlling substrate speed profiles and mask design, these multilayers achieve highly accurate lateral gradients and excellent sagittal thickness uniformity, making them ideal for spectroscopy application at ...
Arindam Majhi +11 more
wiley +1 more source
Development of High‐Performance Multilayer Monochromators
Detailed insights into the optical and multilayer design of Double Multilayer Monochromators (DMM) are presented and fully characterized, including key optimization strategies and solutions to fabrication challenges. By integrating in‐house Ion Beam Figuring and a high uniformity multilayer coating process, the developed DMMs achieve high reflectivity,
Wadwan Singhapong +11 more
wiley +1 more source
Terahertz Volume Plasmon‐Polariton Modulation in All‐Dielectric Hyperbolic Metamaterials
THz volume plasmon‐polariton (VPP) propagation through plasmon‐based hyperbolic metamaterials, made of alternating layers of doped and undoped III‐V semiconductors. Abstract The development of plasmonics and related applications in the terahertz range faces limitations due to the intrinsic high electron density of the standard metals.
Stefano Campanaro +3 more
wiley +1 more source
Vat Photopolymerized HEMA/HEA Hydrogels for Solvent‐Responsive Transparency and Optical Encryption
Vat‐photopolymerized HEMA/HEA hydrogels exhibit reversible transparency‐opacity switching via hydration‐induced microphase separation and solvent exchange. The printed materials enable hydration sensing, optical encryption, and information storage, while maintaining high ductility and reversible rheology.
Murad Ali +4 more
wiley +1 more source
Versatile Gasochromic Hydrogen Detection via Supraparticle‐Based Applied Composite Materials
Silica‐platinum‐resazurin supraparticles are embedded into PMMA to form suprabeads and thin films. The thereby obtained indicators change color from purple to pink to colorless on hydrogen exposure. The indicator systems are tested under various environmental conditions, and their performance is related to their microscopically visualized structure ...
Sarah Wenderoth +7 more
wiley +1 more source

