Results 221 to 230 of about 5,847,780 (255)

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source

Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide survey. [PDF]

Nutr Metab (Lond)
Kim M, Kobori T.
europepmc   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Revealing the protective potential of D-(-)-Quinic acid against thioacetamide-induced hepatic encephalopathy in rats. [PDF]

Sci Rep
Ciftel S, Cicek B, Bolat I, Bulut S, Yildirim S, Suleyman B, Qaniyev M, Süleyman H.   +7 more
europepmc   +1 more source

Interaction between the non-alcoholic fatty liver disease fibrosis score and vitamin D deficiency on left ventricular hypertrophy and impaired diastolic function in patients with type 2 diabetes mellitus. [PDF]

Diabetol Metab Syndr
Li YM, Huang JY, Guo R, Li SM, Chen C, Wu M, Wang R, Liu MY, Yiu KH.   +8 more
europepmc   +1 more source

Modular Synthetic Platform for the Elaboration of Fragments in Three Dimensions for Fragment-Based Drug Discovery. [PDF]

J Am Chem Soc
Gomez-Angel AR, Klein HF, Yao SY, Donald JR, Firth JD, Appiani R, Palmer CJ, Lincoln J, Lucas SCC, Fusani L, Storer RI, O'Brien P.   +11 more
europepmc   +1 more source

Dietary acid load and its association with psychological disorders, sleep quality, and mood among Iranian older adults: a cross-sectional study. [PDF]

BMC Public Health
Mahjourian MM, Abbasi H, Hanjani NA, Hajian PN, Azadbakht L.   +4 more
europepmc   +1 more source