Results 101 to 110 of about 9,073,090 (263)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Exploring Efimov states in D * D * D * and DD * D * three-body systems

open access: yesJournal of High Energy Physics
The Efimov effect is an intriguing three-body quantum phenomenon. Searching for Efimov states within the realms of nuclear and hadronic physics presents a challenge due to the inherent inability of natural physical systems to exhibit adjustable two-body ...
Hai-Long Fu   +6 more
doaj   +1 more source

ОÑврт на два Ñлучаја муковиÑцидоза (Fibrosis Cystica) кај новородено

open access: yes, 2017
Two sucker babies with fibrosa cystic have been presented: in one of them the disease was severe with the lethal outcome, while the other baby could be successfully treated.
СпировÑки (Spirovski), Зоран (Zoran)   +2 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

ЦелоÑно Мобилни?

open access: yes, 2016
изваР...
Глигоров, Зоран
core  

Три Ñлучаи на Syndroma Willi Prader Labhardt во доенечка возраÑÑ‚ [PDF]

open access: yes, 2017
Authors presented three cases of Willi Prader Labhardt Syndroma whose cardinal symptoms are: psychomotor retardation, proportional obesity, hypogenitalism, a small bifrontal circumference, and carp-like mouth.During the pregnancy, children's mothers felt
Гордова-МуратовÑка (Gordova-Muratovska), ÐлекÑандра (Aleksandra)   +2 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Епидемиолошко-клиничка корелација кај заболени од вируÑен хепатит врз клинички материјал

open access: yes, 2016
The epidemiologic-clinical correlation at 170 patients of hepatitis virosa (VH) indicated the following:It is intensify the sessional frequency of ill patients with the evident increase about Jun-August (10.58), and with the extreme top in the course of ...
Караџов (Karadzhov), Зоран (Zoran)   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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