Results 111 to 120 of about 5,871,901 (302)
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
МЕЖБЮДЖЕТ�ЫЕ ОТ�ОШЕ�ИЯ И ОС�ОВ�ЫЕ ��ПР�ВЛЕ�ИЯ ИХ СОВЕРШЕ�СТВОВ��ИЯ (�� ПРИМЕРЕ ГРУЗИИ) [PDF]
The paper considers inter-budgetary relations as one of the most complex and ambiguous spheres of functioning of state institutions of Georgia. The aim is to identify the problematic aspects of Georgia's budget policy and formulate the key directions for
Abuselidze, George
core +3 more sources
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
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openalex +1 more source
The Distance Matrices of Some Graphs Related to Wheel Graphs
Let D denote the distance matrix of a connected graph G. The inertia of D is the triple of integers (n+(D), n0(D), n-(D)), where n+(D), n0(D), and n-(D) denote the number of positive, 0, and negative eigenvalues of D, respectively.
Xiaoling Zhang, Chengyuan Song
doaj +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Компарација на шеÑÑ‚ минутниот теÑÑ‚ на одење кај деца Ñо различни невромуÑкулни болеÑти и здрави деца на возраÑÑ‚ од 5 до 14 години [PDF]
The aim of this study was to determinate the importance of 6MWT in children diagnosed with neuromuscular diseases. We evaluated the distances walked and the level of fatigue manifested.
Sabolik, Vesna+8 more
core +1 more source
Распределение d(n,ω) в классах вычетов [PDF]
В работе устанавливаются условия слабо равномерного распределения значений функции d(n,ω) с вещественным характером Дирихле ω(n) в классах вычетов по составному модулю и приводятся асимптотические формулы.
Широков Б. М.
doaj