Results 121 to 130 of about 6,065,276 (313)

Компарација на шеÑÑ‚ минутниот теÑÑ‚ на одење кај деца Ñо различни невромуÑкулни болеÑти и здрави деца на возраÑÑ‚ од 5 до 14 години [PDF]

, 2017
The aim of this study was to determinate the importance of 6MWT in children diagnosed with neuromuscular diseases. We evaluated the distances walked and the level of fatigue manifested.
Sabolik, Vesna, РуÑтеми (Rustemi), Саранда (Saranda), Сулејман (Sulejman), Сабир (Sabir), Ðнгелкова (Angelkova), Ðаталија (Natalija), ÐÑани (Asani), Елмедина (Elmedina), ÐјдаровÑки (Ajdarovski), Ðмир (Amir), КацарÑка (Kacarska), Розана (Rozana), Далипи (Dalipi), Ðделина (Adelina), Дума (Duma), Филип (Filip)   +8 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Systematics and Faunistics of Neotropical Grapholitini, 1: Dichrorampha Guenée, 1845 (Lepidoptera: Tortricidae)

SHILAP, 2012
Se describen dieciocho especies de Dichrorampha neotropicales (D. obliqua Razowski & Becker, sp. n., D. brusquaea Razowski & Becker, sp. n., D. mnesisocia Razowski & Becker, sp. n., D. atomosa Razowski & Becker, sp. n., D. limae Razowski & Becker, sp. n.,
J. Razowski, V. O. Becker
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

ОÑтеогенеза и рехабилитација кај пертрохантерни фрактури Ñо dynamic hip screw- ДХС [PDF]

, 2017
Ovarian cancer is the fifth leading cause of cancer deaths and has the highest mortality rate among gynecologic cancers in women in North America and Europe.The aim of this study wasto analyze the correlation between E-cadherin expression and clinical ...
ПопоÑка (Poposka), ÐнаÑтаÑика (Anastasika), МитревÑка (Mitrevska), Билјана (Biljana), КоевÑка (Koevska), Валентина (Valentina), ГоцевÑка (Gocevska), Марија (Marija), Гркова-МишковÑка (Grkova Miskovska), Емилија (Emilija)   +4 more
core   +1 more source

Heart disease and stroke statistics--2014 update: a report from the American Heart Association.

Circulation, 2014
A. Go, D. Mozaffarian, V. Roger, E. Benjamin, J. Berry, M. Blaha, S. Dai, E. Ford, C. Fox, Sheila Franco, H. Fullerton, C. Gillespie, S. Hailpern, J. A. Heit, V. Howard, Mark D. Huffman, S. Judd, B. Kissela, S. Kittner, D. Lackland, J. Lichtman, L. Lisabeth, R. Mackey, D. Magid, G. Marcus, A. Marelli, D. Matchar, Darren K Mcguire, E. Mohler, C. Moy, M. Mussolino, R. Neumar, G. Nichol, D. Pandey, N. Paynter, M. Reeves, P. Sorlie, J. Stein, A. Towfighi, T. Turan, S. Virani, N. Wong, D. Woo, M. B. Turner   +43 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

One Method of Solution of an Optimum Investment Portfolio Problem for Risky Assets [PDF]

The problem for choice of an optimum investment portfolio is considered. The square-law form of risk is presented as two-multiple convolution of ковариантного tensor of the covariance matrix and kontravariant vector of weights.
Alexander Milnikov, Mikheil Mamistvalov
core   +1 more source

From the beginning of additional capitalization to July 1, 2017, additional capitalized banks provided the economy with about 13.7 trillion rubles in credits [PDF]

, 2017
Original title in Russian is С начала докапитализации по 1 Ð¸ÑŽÐ»Ñ 2017 Ðó. докапитализированные банки предоÑтавили в Ñкономику порÑдка 13,7 трлн руб.
Russian Federation: Accounts Chamber of the Russian Federation
core   +1 more source