Тенденции в Ð¿Ñ€Ð¾Ð¸Ð·Ð²Ð¾Ð´Ð¸Ñ‚ÐµÐ»Ð½Ð¾Ñ Ñ‚Ñ‚Ð° на труда в Ð±ÑŠÐ»Ð³Ð°Ñ€Ñ ÐºÐ°Ñ‚Ð° минна Ð¸Ð½Ð´ÑƒÑ Ñ‚Ñ€Ð¸Ñ [PDF]
, 2020 Ð’Ðμñ Ðμð Ð ̧Ð ⁄ Ðœð ̧Ñ‚Ðμð
openalex
БезбедноÑта во Ñообраќајот на патиштата – предизвици за јавноздравÑтвен одговор [PDF]
, 2018 Road traffic safety is a high-priority public health problem. In the world annually, around 1.25 million people die on roads as a result of road traffic accidents (2.1% of global mortality), and 20-50 million people are injured and remain with life-long ...
Тозија (Tozija), Фимка (Fimka)
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
ЕФЕКТИ ÐÐ CYP3A4 ГЕÐЕТСКИ ПОЛИМОРФИЗÐÐœ ВРЗ ПОСТОПЕРÐТИВÐÐТРПОТРОШУВÐЧКРÐРФЕÐТÐÐИЛ ПРИ ТРЕТМÐÐ ÐРПОСТОПЕРÐТИВÐÐТРБОЛКР[PDF]
, 2017 Минималната ефективна концентрација на опиоиден аналгетик може значајно да Ñе разликува меѓу пациентите.
СпировÑка, Татјана +8 more
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Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Зачем программирование грамотному человеку? (Ñ Ñ Ñ Ðµ)
, 2012 Ivan Travkin
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Ð¡ÑŠÑ‰Ð½Ð¾Ñ Ñ‚ и Ð¿Ñ€Ð°ÐºÑ‚Ð¸Ñ‡ÐµÑ ÐºÐ¸ Ð¸Ð·Ð¼ÐµÑ€ÐµÐ½Ð¸Ñ Ð½Ð° Ð»Ð¸Ð´ÐµÑ€Ñ Ñ‚Ð²Ð¾Ñ‚Ð¾ в Ð¼ÐµÐ¶Ð´ÑƒÐ½Ð°Ñ€Ð¾Ð´Ð½Ð¸Ñ Ð¼ÐµÐ½Ð¸Ð´Ð¶Ð¼ÑŠÐ½Ñ‚ [PDF]
, 2020 СР̧Ð ⁄ ÐμÐ ⁄ Ð ⁄ СР̧Ð ⁄ ÐμÐ ⁄ Ð ⁄ Ð ⁄ Ð
openalex
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
ДејÑтво на интерферон врз фагоцитоза на леукоцитите во in vitro уÑлови [PDF]
, 2016 In atempt to get elementary insight of interpheron action on leukocyte fagocytable capacity, in vitro were tested fagocytes from the patients with various diseases.
УгринÑки (Ugrinski), Предраг (Predrag) +1 more
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