Results 201 to 210 of about 6,155,332 (265)

Negative feedback regulation of alcohol ingestion through the FGF21-PVH oxytocin-VTA dopamine system. [PDF]

Proc Natl Acad Sci U S A
Matsui S, Takahashi Y, Morioka S, Ozawa T, Kanayama S, Iwama H, Geng L, Umemoto K, Oguri Y, Tsuzuki S, Li Y, Hikida T, Sasaki T.   +12 more
europepmc   +1 more source

« ‚ßÔÎ ×ð´ ×ñ˜æè Öæß

, 2013
àææçÜ×æ ÌÕSâä×
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Fecal Microbiota Transplantation Donor Screening: Is <i>Dientamoeba fragilis</i> a Valid Criterion for Donor Exclusion? A Longitudinal Study of a Swiss Cohort. [PDF]

Microorganisms
Moser K, Ballif A, Pillonel T, Concu M, Montenegro-Borbolla E, Nickel B, Stampfli C, Ruf MT, Audry M, Kapel N, Gerber S, Jacot D, Bertelli C, Galpérine T.   +13 more
europepmc   +1 more source

ÐÑкÑÐ²Ð°Ð½Ð½Ñ Ñ Ð¿ÑоÑÑлакÑика гнÑйно-ÑепÑиÑÐ½Ð¸Ñ ÑÑÐºÐ»Ð°Ð´Ð½ÐµÐ½Ñ Ñа ÑÑоÑепÑиÑÑ Ð¿ÑÑÐ»Ñ Ð´Ð¸ÑÑанÑÑÐ¹Ð½Ð¾Ñ Ð»ÑÑоÑÑипÑÑÑ.

, 2013
С. І. Баранник, І. Д. Крижановський, І. Б. Білий, А. С. Бараннік   +3 more
openalex   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Natural monosaccharide-based piezoelectric supramolecular materials for energy harvesting and information transmission. [PDF]

Chem Sci
Chen S, Yang J, Liu S, Huo Y, Cheng X, Li L, Ji W.   +6 more
europepmc   +1 more source

Зачем программирование грамотному человеку? (Ñ Ñ Ñ Ðµ)

, 2012
Ivan Travkin
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source