Results 191 to 200 of about 8,672,155 (304)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Optimization of L-Arginine to Meet the Dietary Requirement of Juvenile Coho Salmon (<i>Oncorhynchus kisutch</i>). [PDF]

open access: yesAquac Nutr
Yu L   +8 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Distinct mechanisms decommission redundant enhancers to facilitate phenotypic evolution. [PDF]

open access: yesSci Adv
Said-Ahmad A   +6 more
europepmc   +1 more source

ЦенÑÑалÑÐ½Ñ Ð¾Ñгани виконавÑÐ¾Ñ Ð²Ð»Ð°Ð´Ð¸ УкÑаÑни з обÑлÑговÑÐ²Ð°Ð½Ð½Ñ Ð¿Ð¾Ð²ÑÑÑÑного ÑÑÑÑ

open access: green, 2017
Юринець, Юлія Леонідівна; Національний авіаційний університет   +1 more
openalex   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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