Results 251 to 260 of about 8,672,155 (304)

Involvement of trimethylamine N-oxide in major depressive disorder via astrocytic d-Serine dysregulation. [PDF]

open access: yesNeurotherapeutics
Lin L   +12 more
europepmc   +1 more source

ÐÐÐÐРСÐФÐÐÐЦÐЯ ÐÐУЧÐÐÐÐ ÐÐÐÐÐЯ Ð ÐÐФÐРÐÐЦÐÐÐÐУЮ ÐРУ

open access: green, 2009
Дротянко, Л. Г.; Гуманітарний інститут Національного авіаційного університету
openalex   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

THE Т. Т. С. TEST IN QUANTITATIVE DETERMINATION OF BACTERIURIA

open access: green, 1974
Sv. Razboynikov   +4 more
openalex   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Vitamin D as a Regulator of the Biological Clock-Implications for Circadian-Metabolic Dysregulation. [PDF]

open access: yesInt J Mol Sci
Vesković M   +6 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Role of Vitamin D in Chronic Obstructive Pulmonary Disease: Mechanisms and Clinical Implications. [PDF]

open access: yesAm J Lifestyle Med
Aggarwal K   +5 more
europepmc   +1 more source

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