Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Exploring the Link: Vitamin D Levels and Its Clinical Implications in Guillain-Barré Syndrome Patients. [PDF]
Lopez-Pizano A+5 more
europepmc +1 more source
ТермокаталитичеÑкий гидрогенолиз горючих Ñланцев
Zhaksyntay Kairbekov+3 more
openalex
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Association between vitamin D level and insulin resistance among patients with type 2 diabetes mellitus in Sana'a City. [PDF]
Al-Shami AS+3 more
europepmc +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns+2 more
wiley +1 more source
Consumer perspectives on implementing falls prevention and management in rehabilitation hospitals: protocol for a qualitative study. [PDF]
McKercher JP+6 more
europepmc +1 more source
Cинтез в пламени Ñупергидрофобной Ñажи и ее применение
Meruert Nazhipkyzy+7 more
openalex +1 more source
Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski+13 more
wiley +1 more source
The Effect of Vitamin D3 Supplementation on the Incidence of Diagnosed Dementia Among Healthy Older Adults-The Finnish Vitamin D Trial. [PDF]
Lönnroos E+9 more
europepmc +1 more source