In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen+13 more
wiley +1 more source
A Historical Writing Apprenticeship for Adolescents: Integrating Disciplinary Learning With Cognitive Strategies [PDF]
This study explored the extent to which an 18â day history and writing curriculum intervention, taught over the course of one year, helped culturally and academically diverse adolescents achieve important disciplinary literacy learning in history ...
Croninger, Robert+5 more
core +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
ОÑтеогенеза и рехабилитација кај пертрохантерни фрактури Ñо dynamic hip screw- ДХС [PDF]
Ovarian cancer is the fifth leading cause of cancer deaths and has the highest mortality rate among gynecologic cancers in women in North America and Europe.The aim of this study wasto analyze the correlation between E-cadherin expression and clinical ...
ПопоÑка (Poposka), ÐнаÑтаÑика (Anastasika)+4 more
core +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
Ја загубивме битката за работната површина, тврди IBM [PDF]
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информатика, МЕДИС -
core +1 more source
Letter: Changes in Blood Lactates during Ergometric Testing on Professional Football Players during One Half Season Competitions (Maced Med Electr J. 2015 Oct 02; 2015;50012. http://dx.doi.org/10.3889/mmej.2015.50012) [PDF]
ПоднеÑени Ñе забелешки од ИнÑтитутот за физиологија при МедицинÑкиот факултет во Скопје за автентичноÑта, плагијаризмот и другите етички Ð¾Ñ ...
Spiroski, Mirko
core +2 more sources
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke+12 more
wiley +1 more source
СиÑтемÑки Ð»ÑƒÐ¿ÑƒÑ ÐµÑ€Ð¸Ñ‚ÐµÐ¼Ð°Ñ‚Ð¾Ð·ÑƒÑ (СЛЕ) не е невообичаена ÑоÑтојба. Повеќето невролози Ñе ÑвеÑни дека Ñ‚aa може да предизвика широк Ñпектар на невроР...
Bundovska, Smiljana, Kuzmanovska, Dafina
core +2 more sources
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić+31 more
wiley +1 more source