Results 111 to 120 of about 332 (162)
Droplet Digital CRISPR for Nucleic Acid Detection
Advanced Science, EarlyView.This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang +4 more
wiley +1 more source
Experimental Joint Estimation of Phase and Phase Diffusion Via Deterministic Bell Measurements
Advanced Science, EarlyView.This work employs Bell measurement, a form of entangling measurement, to estimate both the phase and its fluctuations in an optical interferometer. By incorporating a novel quantum effect at the measurement stage, the proposed method achieves the ultimate precision limit and demonstrates the significant potential of entangling measurements in multi ...
Ben Wang +4 more
wiley +1 more source
Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Advanced Science, EarlyView.Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang +10 more
wiley +1 more source
Advanced Science, EarlyView.An irreversible acid‐responsive radioluminescence memory scintillator, Zn1.3Ga1.4Ge0.3O4:Cr3+@Zn2GeO4:Eu3+ (ZGGO@ZGO), is developed in this work. The engineered dual‐layer security system composed of ZGGO@ZGO and ZGO achieves a combined effect of visual misdirection and sequential logic gates requiring acid treatment and CCD detection, significantly ...
Lin Liu +7 more
wiley +1 more source