Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Pulsatile sequential drug release system for cascade tumor deep penetration and differentiation therapy to enhance chemoimmunotherapy. [PDF]
Liu F+14 more
europepmc +1 more source
Данъчни Ñ Ñ‚Ð¸Ð¼ÑƒÐ»Ð¸ за Ð½Ð°ÑƒÑ‡Ð½Ð¾Ð¸Ð·Ñ Ð»ÐµÐ´Ð¾Ð²Ð°Ñ‚ÐµÐ»Ñ ÐºÐ°Ñ‚Ð° и развойна Ð´ÐµÐ¹Ð½Ð¾Ñ Ñ‚ в Ñ Ñ‚Ñ€Ð°Ð½Ð¸Ñ‚Ðµ от ОИСРи ЕС [PDF]
ЛР̧Ð Ð ̧Ñ Ð”Ð°Ð ⁄ Ñ Ð ⁄ Ð ⁄ Ра
openalex
Electron cloud simulations: build-up and related effects [PDF]
Rumolo, Giovanni, Zimmermann, Frank
core +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Central Neurophysiological Alterations in Dystrophic mdx Mice Correlate With Reduced Hippocampal Levels of the Endogenous NMDA Receptor Ligand D-Aspartate. [PDF]
Mastrostefano F+6 more
europepmc +1 more source
ÐŸÑ€ÐµÐ´Ð¸Ð·Ð²Ð¸ÐºÐ°Ñ‚ÐµÐ»Ñ Ñ‚Ð²Ð° при проектиране, изграждане и ÐµÐºÑ Ð¿Ð»Ð¾Ð°Ñ‚Ð°Ñ†Ð¸Ñ Ð½Ð° Ð¿Ð°Ñ Ð¸Ð²Ð½Ð° Ñ Ð³Ñ€Ð°Ð´Ð° в Ð‘ÑŠÐ»Ð³Ð°Ñ€Ð¸Ñ [PDF]
Ð ̄Ð Ð ⁄ Ñ€ СтР⁄ Ñ Ð ⁄ Ð ⁄ Ð
openalex
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Biofilm Formation and Antibiotic Resistance Genes of Escherichia coli From Poultry Farms and Clinical Samples. [PDF]
Sasoon A+8 more
europepmc +1 more source