Results 121 to 130 of about 8,825,592 (258)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
ИÑторијатот на македонÑката хирургија
, 2016 ИзваР...
Серафимов (Serafimov), Кочо (Kocho)
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2018 Congenital anomalies of the kidney and urinary tract- CAKUT are common childhood pathology accounting for 20-30% of all perinatally detected congenital anomalies. The importance of CAKUT is the risk they represent to kidney function deterioration and end-
ПапазовÑка-ЧерепналковÑки (Papazovska-Cherepnalkovski), Ðнет (Anet) +6 more
core
European Physical Journal C: Particles and FieldsAs a D-wave partner of $$\psi (3770)$$ ψ ( 3770 ) identified by the LHCb Collaboration, $$\psi _3(3842)$$ ψ 3 ( 3842 ) lies between the $$D{\bar{D}}$$ D D ¯ and $$D\bar{D^*}$$ D D ∗ ¯ thresholds.
Zi-Yue Bai +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 2016 The pertechnetate concentrating mechanism in thyroid gland, salivary glands and stomach was studied in rats by determination tissue: plasma radioactivity ratio.
Серафимов (Serafimov), Ðикола (Nikola) +2 more
core