Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Telemedicine use in medical facilities for rural medical care and local governments in Japan. [PDF]
Matsubara D +5 more
europepmc +1 more source
Effect of exercise on hormonal responses in adolescents with obesity and leptin resistance: a randomized trial. [PDF]
Jeong D +5 more
europepmc +1 more source
Effect of calcium and vitamin D supplementation on recurrence of benign paroxysmal positional vertigo in osteoporotic patients. [PDF]
Wang Z, He G, Chen Z, Jie H, Zeng Q.
europepmc +1 more source
D-mannose alleviates rotenone-induced PD mouse model through microbiota-gut-brain axis. [PDF]
Hong Y, Ge C, Jin J, Gao Y, Tang Y.
europepmc +1 more source
Bicuspid Aortic Valve: Old and Novel Gene Contribution to Disease Onset and Complications. [PDF]
Sticchi E +16 more
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Fecal Microbiota Transplantation Donor Screening: Is Dientamoeba fragilis a Valid Criterion for Donor Exclusion? A Longitudinal Study of a Swiss Cohort. [PDF]
Moser K +13 more
europepmc +1 more source
Design, synthesis, structural characterization, anticancer evaluation, and computational studies of novel quinoline-1,2,3-triazole glycohybrids. [PDF]
Kumar R +4 more
europepmc +1 more source

