Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Degree sequence for k-arc strongly connected multiple digraphs
Journal of Inequalities and Applications, 2017 Let D be a digraph on { v 1 , … , v n } $\{v_{1},\ldots, v_{n}\}$ . Then the sequence { ( d + ( v 1 ) , d − ( v 1 ) ) , … , ( d + ( v n ) , d − ( v n ) ) } $\{ (d^{+}(v_{1}), d^{-}(v_{1})), \ldots, (d^{+}(v_{n}), d^{-}(v_{n}))\}$ is called the degree ...
Yanmei Hong, Qinghai Liu
doaj +1 more source
Животниот Ñтил и контрола на хроничните незаразни болеÑти [PDF]
, 2018 Non-communicable diseases, also known as modern-life diseases, are the leading cause of morbidity and mortality in the world and in the Republic of Macedonia. The complexity of their occurrence, often associated with multifactorial etiology and lifestyle
СпаÑовÑки (Spasovski), Моме (Mome) +3 more
core +1 more source
The Role of Metabolic Syndrome in the Development and Progression of Chronic Renal Failure [PDF]
, 2015 Метаболичкиот Ñиндром Ñтанува Ñе поголем здравÑтвен проблем во Ñветот, како во земјите во развој така и во виÑоко развиените земји.
Barjaktarova Prosheva, Tatjana +1 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
ЕВÐЛУÐЦИЈРÐРПРОГРÐМИТЕ ЗРПРЕВЕÐЦИЈРÐÐ ÐœÐЛИГÐИ ÐЕОПЛÐЗМИ ВО РЕПУБЛИКРМÐКЕДОÐИЈР(2005-2015) [PDF]
, 2017 БолеÑти на Ñовремениот живот и водечка причина за морбидитет и морталитет во Република Македонија и во Ñветот Ñе хроничните незаразни болеÑÑ‚
СпаÑовÑки, Моме +1 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
N. A. Polevojaus laiškai S. D. Poltorackiui
Literatūra (Vilnius), 1966 Nikolajus Aleksejevičius Polevojus (1796–1846), žinomas „Maskvos telegrafo" redaktorius ir leidėjas, vienas iš žymesniųjų V. G. Belinskio pirmtakų, rusų XIX a. literatūroje buvo antidvarininkiškos literatūros kritikos pradininkas. Jis pradėjo
V. Salinka
doaj +1 more source
Letter: Changes in Blood Lactates during Ergometric Testing on Professional Football Players during One Half Season Competitions (Maced Med Electr J. 2015 Oct 02; 2015;50012. http://dx.doi.org/10.3889/mmej.2015.50012) [PDF]
, 2015 ПоднеÑени Ñе забелешки од ИнÑтитутот за физиологија при МедицинÑкиот факултет во Скопје за автентичноÑта, плагијаризмот и другите етички Ð¾Ñ ...
Spiroski, Mirko
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source