Results 81 to 90 of about 609 (189)

РазÑабоÑка бизнеÑ-плана пÑедпÑиÑÑиÑ

, 2017
Анастасия Сергеевна Цыганова
openalex   +1 more source

Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways

Advanced Science, EarlyView.
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang, Xinyu Mao, Yu He, Qingshen Jia, Yiding Zhao, Xiaomeng Dai, Xiaoyan Li, Shengyi Sun, Xiaoyan Sheng, Dan Ding, Yuan Shi, Qian Gao, Ling Shuai   +12 more
wiley   +1 more source

Evidence from CD spectra and melting temperatures for stable Hoogsteen-paired oligomer duplexes derived from DNA and hybrid triplexes. [PDF]

Nucleic Acids Res, 1999
Hashem GM, Wen JD, Do Q, Gray DM.
europepmc   +1 more source

Ðнализ влиÑÐ½Ð¸Ñ ÑезÑлÑÑаÑов деÑÑелÑноÑÑи доÑеÑÐ½Ð¸Ñ Ð¾ÑганизаÑий на показаÑели ÑинанÑовой оÑÑеÑноÑÑи Ñ Ð¾Ð»Ð´Ð¸Ð½Ð³Ð°

, 2017
Елизавета Вадимовна Попкова
openalex   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

Advanced Science, EarlyView.
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot, Laure Stickel, Pascal Martin   +2 more
wiley   +1 more source

Classical Path Methods in Line Broadening. I. The Classical Path Approximation. [PDF]

J Res Natl Bur Stand A Phys Chem, 1969
Smith EW, Vidal CR, Cooper J.
europepmc   +1 more source

ÐоÑвÑд малоÑнвазивного лÑкÑÐ²Ð°Ð½Ð½Ñ Ð³Ð½Ñйно-деÑÑÑÑкÑÐ¸Ð²Ð½Ð¸Ñ Ð·Ð°ÑвоÑÑÐ²Ð°Ð½Ñ Ð½Ð¸Ñок Ñа паÑанеÑÑалÑÐ½Ð¾Ñ ÐºÐ»ÑÑковини

, 2015
А. В. Цепінь, А. І. Мисак, В. В. Твердохліб   +2 more
openalex   +2 more sources

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Advanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J. Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, Konstanze F. Winklhofer   +10 more
wiley   +1 more source

РазÑабоÑка ÑÑÑаÑегии пÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ ÐÐÐÐУ Â«Ð¡Ð°Ñ Ð°Ð»Ð¸Ð½Ñкий базовÑй медиÑинÑкий колледж»

, 2017
Ольга Сергеевна Махновская
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source