Results 161 to 170 of about 6,308,764 (249)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Улога на тиреоидното ткиво на блаÑÑ‚-транÑфорамцијата на лимфоцитите на болни Ñо тиреотокÑикоза

open access: yes, 2017
It has been examined the possibility of thyroid tissue as to how as a same antigen influence on blast - transformation, eventually on previously sensitised lymphocytes at thyrotoxicosis patients.The lymphocytes have been separated (taken) from the vein ...
Малинова (Malinova), Љубинка (Ljubinka)   +1 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ðрхивы иÑтории, архивы памÑти. Графика ÐоÑми ЭÑканделла

open access: yes, 2019
The aim is of this research is to reconstruct the poetic and political discourse of plastic artist Noemí Escandell (1942-2019) by analyzing the formats, use of photographic archives and narrative thickness of her works created by the end of the sixties ...
Lucero, María Elena
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Бихејвиор терапија во третманот на фобично-анкÑиозни ÑоÑтојби

open access: yes, 2017
It has been described the use of systematic desensitisation in the treatment of monosymptomatic phobias. The technique of suggestion with medicaments was used.
Петров (Petrov), Златко (Zlatko)   +2 more
core  

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