Results 251 to 260 of about 5,874,846 (297)

Modelling US health equity impacts of emicizumab for severe haemophilia A: aggregate distributional cost-effectiveness analysis. [PDF]

BMJ Open
Majda T, Lee JS, Curtis R, Kowal SL.
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Improvements in Serum 25(OH)D Following Stoss Dosing in People With Cystic Fibrosis and Variable Adherence to Maintenance Regimens: A Retrospective Chart Review. [PDF]

Health Sci Rep
Gordon K, Chapman CG, Harklau NM, Ode KL, Wright BA.   +4 more
europepmc   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Conserved function of the HAUS6 calponin homology domain in anchoring augmin for microtubule branching. [PDF]

Nat Commun
Würtz M, Tonon G, Vermeulen BJA, Zezlina M, Gao Q, Neuner A, Seidl A, König M, Harkenthal M, Eustermann S, Erhardt S, Lolicato F, Schiebel E, Pfeffer S.   +13 more
europepmc   +1 more source

Nitric oxide‐forming nitrite reductases in the anaerobic ammonium oxidizer Kuenenia stuttgartiensis

FEBS Open Bio, EarlyView.
Anammox bacteria remove fixed nitrogen from their environment via anaerobic ammonium oxidation (anammox) with nitrite as electron acceptor and dinitrogen gas as product. The first anammox step is the conversion of nitrite to nitric oxide by nitrite reductase.
Femke J. Vermeir, Lotte W. Nijman, Robert S. Jansen, Laura van Niftrik, Wouter Versantvoort   +4 more
wiley   +1 more source

Femtosecond-Laser-Assisted Liquid-Interface vs Vacuum-Trephine Keratoplasty: A Comparison of 2 Different Techniques - Retrospective Data Analysis. [PDF]

Clin Ophthalmol
Klimek M, Steiner I, Donner R, Skorpik C, Aschauer J, Schmidinger G, Lammer J.   +6 more
europepmc   +1 more source

Скрининг за Ð´Ð¸Ñ˜Ð°Ð±ÐµÑ‚ÐµÑ Ñ‚Ð¸Ð¿ 2 во примарна здравÑтвена заштита

, 2015
Дарко Илиев, Петранка Мишевска, Наташа Илиева   +2 more
openalex  

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Revealing the protective potential of D-(-)-Quinic acid against thioacetamide-induced hepatic encephalopathy in rats. [PDF]

Sci Rep
Ciftel S, Cicek B, Bolat I, Bulut S, Yildirim S, Suleyman B, Qaniyev M, Süleyman H.   +7 more
europepmc   +1 more source